ID   A0A124IPM6_9FIRM        Unreviewed;       260 AA.
AC   A0A124IPM6;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Thiamine pyrophosphate enzyme TPP-binding domain-containing protein {ECO:0000259|Pfam:PF02775};
GN   ORFNames=APF81_23070 {ECO:0000313|EMBL:KUO75816.1};
OS   Desulfosporosinus sp. BRH_c37.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfosporosinus.
OX   NCBI_TaxID=1734396 {ECO:0000313|EMBL:KUO75816.1, ECO:0000313|Proteomes:UP000053148};
RN   [1] {ECO:0000313|EMBL:KUO75816.1, ECO:0000313|Proteomes:UP000053148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c37 {ECO:0000313|EMBL:KUO75816.1};
RA   Bagnoud A., Chourey K., Hettich R.L., De Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUO75816.1}.
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DR   EMBL; LOEW01000144; KUO75816.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A124IPM6; -.
DR   Proteomes; UP000053148; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd03375; TPP_OGFOR; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   PANTHER; PTHR48084:SF1; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          41..181
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
SQ   SEQUENCE   260 AA;  28213 MW;  F270F7ABDABDBCBE CRC64;
     MWCSGCGNGI VLSALLRAFE ELGYKNEDTV VVTGIGCWGK ADDYLTTNAL HTTHGRALAY
     ATGVKAVNPK LHVVVLMGDG DSVTIGGNHF IHAARRNIDL TAIVVNNFNF GMTGGQFSAT
     TPAESFTSTT AYGNPERQLD ICALAEVAGA NYVARETVYN GRMLQTYIKE ALSKKGFSIV
     EAVSPCSTHY GSKNRLKVPI TFLRWLKEKG VSREEYLEIP AAGEQGYFIT GKLVDRNAPD
     FSTQYEEIRR RAMGALGAAK
//