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Database: UniProt
Entry: A0A124IVN9_9BACL
LinkDB: A0A124IVN9_9BACL
Original site: A0A124IVN9_9BACL 
ID   A0A124IVN9_9BACL        Unreviewed;       302 AA.
AC   A0A124IVN9;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=ATW55_10620 {ECO:0000313|EMBL:KUO94850.1};
OS   Acidibacillus ferrooxidans.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Acidibacillus.
OX   NCBI_TaxID=1765683 {ECO:0000313|EMBL:KUO94850.1, ECO:0000313|Proteomes:UP000053557};
RN   [1] {ECO:0000313|EMBL:KUO94850.1, ECO:0000313|Proteomes:UP000053557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ITV001 {ECO:0000313|EMBL:KUO94850.1,
RC   ECO:0000313|Proteomes:UP000053557};
RA   Dall'Agnol H., Nancucheo I., Johnson B., Oliveira R., Leite L.,
RA   Pylro V., Nunes G.L., Tzotzos G., Fernandes G.R., Dutra J.,
RA   Orellana S.C., Oliveira G.;
RT   "Draft genome sequence of Acidibacillus ferrooxidans ITV001, isolated
RT   from a chalcopyrite acid mine drainage site in Brazil.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUO94850.1}.
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DR   EMBL; LPVJ01000070; KUO94850.1; -; Genomic_DNA.
DR   RefSeq; WP_067719634.1; NZ_LPVJ01000070.1.
DR   EnsemblBacteria; KUO94850; KUO94850; ATW55_10620.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000053557; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053557};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254}.
FT   DOMAIN        2    184       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      211    289       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        177    177       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   302 AA;  33489 MW;  0D2C8703542591ED CRC64;
     MKIGYLGPVG TYSHRAATWL ADAYGLHAAM LTPYPSILDL LDGLDQHEIY AAIAPLENSI
     EGSVLVTLDR LRLCLMTIRA ELTIPIRHSV FILPDAKQSE IRVVRSHPQA LAQCRNTLRR
     LFPAARHEDA DSTAGALHSI VKEGDRTLAA VGSFEAGRDL PLVRIVEDAQ DHPYNETRFA
     LLTRRATGNS EDAFASFKMI KRIPEYQKTS ILLELGDDHP GALFEVLRIL ARDSINLSKL
     ESRPSRRGLG SYHFFLDLLL QSDSGEVEQA LAEIATLTGF VLHTIGSYPC FREDADETVS
     QK
//
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