ID A0A124PBK1_9BURK Unreviewed; 563 AA.
AC A0A124PBK1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:KVE35049.1};
GN ORFNames=WS68_07980 {ECO:0000313|EMBL:KVE35049.1};
OS Burkholderia sp. TSV86.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1385594 {ECO:0000313|EMBL:KVE35049.1, ECO:0000313|Proteomes:UP000066043};
RN [1] {ECO:0000313|EMBL:KVE35049.1, ECO:0000313|Proteomes:UP000066043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSV86 {ECO:0000313|EMBL:KVE35049.1,
RC ECO:0000313|Proteomes:UP000066043};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVE35049.1}.
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DR EMBL; LOWB01000078; KVE35049.1; -; Genomic_DNA.
DR RefSeq; WP_059571453.1; NZ_LOWB01000078.1.
DR AlphaFoldDB; A0A124PBK1; -.
DR Proteomes; UP000066043; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968}.
FT DOMAIN 88..111
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 262..276
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 90
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 563 AA; 61537 MW; AE9801A0F119833B CRC64;
MVAERTPEGE FDYVIVGAGT AGCVLASRLS EERDVSVLLI EAGGNDDYRW IHIPVGYLYC
IGNPRTDWRY KTEPEAGLNG RALSYPRGRV LGGSSSINGM IYMRGQRDDY DGWARATGDD
GWSWNAVLPI FKRSEDHHAG ASDAHGAGGP WRVEKQRLRW EILEAFSQAA QQTGISATDD
FNRGDNAGVG YFEVNQKRGV RWNASKAFLR PALARPNLTV VTGARAERLV FDARRCVGVQ
YRRDDGSRCV ARARAEVLLA SGAVNSPQLL ELSGIGDGER LHALGIEVMH ALRGVGENLQ
DHLQLRMAFR VRGVRTLNTL AAHWWGKLMI AAQYALTKSG PMSMAPSQLG AFAKSDQHDP
ALTRPDLEYH VQPLSLERFG EPLHRFNAFT ASVCHLRPTS RGSIHAVSPD PARAPAIAPN
YLSTDHDRRV AANALRLTRR IAAAPALARY APEEILPGAH YQSEEQLIEA AGAVGTTIFH
PVGTCRMGRA DDPDAVVDSR LRVRGVTGLR VVDASVMPAI TSGNTNSPTL MIAERASDMI
RADRRGVAQR DDAMTWPETA TPI
//
