ID A0A125A1I9_9FLAO Unreviewed; 605 AA.
AC A0A125A1I9;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN Name=pcrA_1 {ECO:0000313|EMBL:KVV16328.1};
GN ORFNames=AP058_00119 {ECO:0000313|EMBL:KVV16328.1};
OS Flavobacterium sp. TAB 87.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1729581 {ECO:0000313|EMBL:KVV16328.1, ECO:0000313|Proteomes:UP000059935};
RN [1] {ECO:0000313|EMBL:KVV16328.1, ECO:0000313|Proteomes:UP000059935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAB87 {ECO:0000313|EMBL:KVV16328.1,
RC ECO:0000313|Proteomes:UP000059935};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVV16328.1}.
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DR EMBL; LLWK01000020; KVV16328.1; -; Genomic_DNA.
DR RefSeq; WP_066305584.1; NZ_LLWK01000020.1.
DR AlphaFoldDB; A0A125A1I9; -.
DR STRING; 1729581.AP058_00119; -.
DR PATRIC; fig|1729581.3.peg.131; -.
DR OrthoDB; 1100019at2; -.
DR Proteomes; UP000059935; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF3; ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000059935}.
FT DOMAIN 1..303
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 22..29
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 605 AA; 70158 MW; 8697CAB3AD3CF64B CRC64;
MYFLNEERLA YLNARGKIIL NACPGSGKTT TIAKKILDLE NLKEIGDHSG VACLSFTNSA
KDEINEAYKK MSGKSLQFPN HVSTIDSFIN KFITLPFYNL LNRDFNRPKI LDHTTILNDM
WKTTYIKNGK TLEGLLRPLN NAEYKAQNNR SIFHLYPPSE IRIEPNGTFS INGNKPSLEK
VEKTSFDNYC KLIKNTQFKK GLISTSDSAF IALHLLKNNP KICEWLSLRF PFIIIDEAQD
NSLMQHAIFE ELIKQGLKNI ELIGDPYQSL YQWRDAKPEE FLRKYDTDET WQSFDLTDNR
RSPQSIIDVF SKIRRQNDSN IKSLDCKELE ESIVLYKYST TNHQLIIKHY DDYCAKNKYI
NSCIVVRGNS LKDSLLGKKS EQRPWGIQLP KNIIFAKNLY ISGDLKNAIK DIRSVCISLI
YSEITDYHKL KDIEKEKSLD PNFNSLMITV LDELPDFTKT IKDWTIETQL FIKKKLNLTS
DIDFSLRNRK STYLEKSTLT ESVESHFKKS YSTLNIPITT IHQVKGQTLD SILVFFNEKK
HKDNITFENI SNTENVFPDE NKRLIYVALS RPKHLLAIAF PKSITDEELK KKFGEKIRII
KEDEL
//
