ID A0A125JRX4_9BURK Unreviewed; 824 AA.
AC A0A125JRX4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:KWK67972.1};
GN ORFNames=WM16_26265 {ECO:0000313|EMBL:KWK67972.1};
OS Burkholderia ubonensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=101571 {ECO:0000313|EMBL:KWK67972.1, ECO:0000313|Proteomes:UP000065504};
RN [1] {ECO:0000313|EMBL:KWK67972.1, ECO:0000313|Proteomes:UP000065504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSMB782WGS {ECO:0000313|EMBL:KWK67972.1,
RC ECO:0000313|Proteomes:UP000065504};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWK67972.1}.
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DR EMBL; LPLU01000120; KWK67972.1; -; Genomic_DNA.
DR RefSeq; WP_060238264.1; NZ_LPLU01000120.1.
DR AlphaFoldDB; A0A125JRX4; -.
DR Proteomes; UP000065504; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 570..766
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 824 AA; 87655 MW; 55864DCA9BE284F1 CRC64;
MRVWWVAFAF GVAVLQRQAA LPGVAHWLGG AAVLAALAAA GIGCARRRPR TRATAAIGWT
LWAAAACVVG FGYAAGRAEW RLRDALPAEW EGRDITVTGV IKGLPAVDDA GARFLFAVES
NDAGLTRFPP LIRLSWRTYG ARGEPAAAPD LRAAQRWRLT VRLKRPHGEA NPGVRDSEAA
WLGAGIRALG YVSAPQRAAL LDARARGIQA SIDRQRDRLR ARIVATLGQH ADHRGIVAAL
AIGDQSGIGG DDWRVLRNTG TSHLVAISGL HVGLVGGIAG WLASAVWRRL RWRGRAAVLV
VPAPWVAALA ALTGALGYAA LAGFNVPAQR SWWMIAAGGV AYLAGRSVPA SSVLCAALGA
VLLADPWAVL SAGFWLSFGA VAVILLAVSG WRAVQEPGAE PEGAGFGERL RAWRRRAIRR
AAEASRVQYA VTIGLAPLTA AWFAQISVSG PLANAFAIPW VSSVVTPIVL AGIALPAPLD
AAAFRLARAS LDPMMAALER LADWPRSVFW LPMPDWPVLT LACVGVAWVL LPRGWPLRWA
APLTWLPLVA PAPDRPPEGG FRLTVVDVGQ GAAVLVETAR RTLLFDAGPG AESTHAGERI
VAPFLRARGI RDLDTLVLSH ADADHAGGAP AVYAAVEVRQ LLGGMPAGHR LWRDAQAAGV
ASRVPCAAGQ RWRWDGVTFT MLWPQGGPDG GATNAQSCVL RVDAGGTSAL LTGDIEARVE
RRLVDTDRAA LAAQILVVAH HGSRTSSVEP FLDSVGPRVA VFPVGYRNRF GHPHRTVLAR
FAARGIPLPR TDRDGAVRFD VAPADGRFAL ELHRDAQRRY WMDR
//
