ID A0A125PHK6_9BASI Unreviewed; 1624 AA.
AC A0A125PHK6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Kinesin-domain-containing protein {ECO:0000313|EMBL:KWU41614.1};
DE Flags: Fragment;
GN ORFNames=RHOSPDRAFT_6029 {ECO:0000313|EMBL:KWU41614.1};
OS Rhodotorula sp. JG-1b.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1305733 {ECO:0000313|EMBL:KWU41614.1, ECO:0000313|Proteomes:UP000062823};
RN [1] {ECO:0000313|EMBL:KWU41614.1, ECO:0000313|Proteomes:UP000062823}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JG-1b {ECO:0000313|EMBL:KWU41614.1,
RC ECO:0000313|Proteomes:UP000062823};
RG DOE Joint Genome Institute;
RA Goordial J., Raymond-Bouchard I., Riley R., Ronholm J., Shapiro N.,
RA Woyke T., Grigoriev I.V., Labutti K.M., Greer C., Whyte L., Bakermans C.;
RT "Draft genome of eurypsychrophile Rhodotorula sp. JG1b isolated from
RT permafrost in the hyper-arid Upper Elevation McMurdo Dry Valleys,
RT Antarctica.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KQ954531; KWU41614.1; -; Genomic_DNA.
DR STRING; 1305733.A0A125PHK6; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000062823; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000062823}.
FT DOMAIN 4..366
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 524..582
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 1533..1624
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 629..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1495..1523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 108..115
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KWU41614.1"
FT NON_TER 1624
FT /evidence="ECO:0000313|EMBL:KWU41614.1"
SQ SEQUENCE 1624 AA; 179831 MW; 8CA62BF5E90F5B58 CRC64;
GGGNIKVVVR CRPLNQREIA RGAKCLVRME GNHTFLDPPD AILQVANMTS GRATEKETKS
FAFDKSYWSA CPKDDPAYAS QQTLFNDLGR DLLDHAFEGY NTTVFAYGQT GSGKSYSMMG
YGSDRGIIPL ICEALFERIE NRTAESGGDV SFTVEVSYTE IYQEKVRDLL NPSNNNKGSL
KVREHPTLGP YVENLSKCAV QNFEDVERLM DEGTKARTVA ATNMNETSSR SHAVFTLLLT
QKRLDPTTSM VGEKVSRISL VDLAGSERAN STGATGTRLK EGALINKSLT TLGRVIAALA
QASSAPAGKA AKAAADKVPY RDSVLTWLLK DSLGGNSKTA MIAAISPADY EETLSTLRYA
DQAKKIQNKA VVNEDPNAKL IRELKEELET LRARMAGPAT FGGGSPSMLT MNGFHDESTF
DDSVPPERQM VQYKTASGEI KTISKAELQD QLEASEKLMA SVTETWEQKL EKTKEVQLER
ERALESLGIT IEKNLLGVHT PKKMPHLVNL NEDPLMSECL IYQIKRGRTT VGNMDSDRPA
DIKLSGPSIQ DDHCYFECTD DDNKVTLHAG PKGTTMVNGQ RLAPGSVKEL RSGFRVILGD
FHIFRFNHPE EVRRARLTKS RQEVRSPLAA LVDESSATSS PSGTRPDSPM GFAAEDAAVD
WSYARREAVV ARLNSRDVNL DQLNDVDLNQ LYSNILRVRH SRTSSSMAGS DRPESRMSFL
DSVTEDGDGD DDEGEGTASS SRRGSRVRPP SAATWSTDAT SLADSPLTLR HLPDLEEKGF
TFDDVPTRSA LLPPSVTSST ADEEALREKR VMEEKLRKLE TRMAVQRRRL ARLRTTGSSG
SGSSVSDPDA WLDEWPSLTP EEEPLARRVA RVWRRQRRVQ MAEDALSQAV LLKEANVMSR
ELQKGVTFQF ANVERPPPIS ACDHVAGIDE LDNVEDPALH DCIKPCVGVK VLDRRHQAIS
IWSVSKLQRR VQQMREQYRW LDKPEYRQHL VSQDPFYELP PPPGGFSHVA TGLVSLLPLV
RRTTSVQIIQ LYSPYIADPI GTCRIRLQPV EAARTPKMGR VSLPDDDASE FLLVDLAIDE
VCGFDKSEFA ALHLQTSLAD LIDYEDSTGG LAISETVHLD EASAGNLTLE HRFCVPITPA
IEDSLRNKLG AIHVFARPRL SHFDKIDRWD EAREGPRIAS AGVRGGDPSH TDVTRRPETE
LISAQQHDVI AHVEIRELGE KGEYDPVQVV SANRLDAGAF FLRQGLQRRL VLGLSHNSGR
ELAWRRVSKV SLGNVRLLDQ RGLVHASTST IDVELRGIGT PRPEYSKDGM SLLNFAAAWD
SSAHDSPHLN RPTPSGSRAL VQLSFEVEVA GCVAPIPFSV DLAVTIAGRD ARSPSRFTTL
FSSSRLATRV AAVFCVSLRP YQTRKAADIW RLDTSETYVR GEEILSGWRP RGLSLIRDYD
ATTSARRKLA DLEATKAVLA TFWETVPSTT GQDGHTLLSR ALALWQKRFG TNAEVSEPPA
QTMADSKITA PDSAPRRPVQ KTGSAALVPR TETANKRGLL AMLRDPTSSE WRKHWFVLRR
PYLYIYNSAS ELDEAAVINV STVRVEQTPE IEQMLERKFA FAIFTQHNSY FFAAPSYREM
VDWT
//
