ID   A0A125R919_9VIRU        Unreviewed;      2075 AA.
AC   A0A125R919;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   08-NOV-2023, entry version 25.
DE   SubName: Full=Polyprotein {ECO:0000313|EMBL:AMD16208.1};
OS   Sclerotinia sclerotiorum deltaflexivirus 1.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Deltaflexiviridae; Deltaflexivirus;
OC   Sclerotinia deltaflexivirus 1.
OX   NCBI_TaxID=1788309 {ECO:0000313|EMBL:AMD16208.1, ECO:0000313|Proteomes:UP000241608};
RN   [1] {ECO:0000313|EMBL:AMD16208.1, ECO:0000313|Proteomes:UP000241608}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX19 {ECO:0000313|EMBL:AMD16208.1};
RA   Li K., Xie J., Cheng J., Fu Y., Jiang D.;
RT   "A novel positive single-stranded RNA mycovirus isolated to Sclerotinia
RT   sclerotiorum.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KT581451; AMD16208.1; -; Genomic_RNA.
DR   Proteomes; UP000241608; Genome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008174; F:mRNA methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   CDD; cd23248; Deltaflexiviridae_RdRp; 1.
DR   InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR   InterPro; IPR002588; Alphavirus-like_MT_dom.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR   Pfam; PF01443; Viral_helicase1; 1.
DR   Pfam; PF01660; Vmethyltransf; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS51743; ALPHAVIRUS_MT; 1.
DR   PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000241608};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   TRANSMEM        42..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        621..646
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        658..678
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        719..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          234..401
FT                   /note="Alphavirus-like MT"
FT                   /evidence="ECO:0000259|PROSITE:PS51743"
FT   DOMAIN          1842..1949
FT                   /note="RdRp catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50507"
SQ   SEQUENCE   2075 AA;  230680 MW;  A07C2A6599D1684E CRC64;
     MKSKYNRLDP TRGMSLSLSL VAVLAATVHI YASATAPLLW YILVPFLLSA TAAIYVPALL
     FSVIVTLAVL HITTYSFLLM CGAKIKSSPP NTPGFCWHTV VPENYRHRFS YNPEGWICQK
     KLKEILLFKI RYHKDPSSRF PFVRLISLGQ SQYHILPYTS YKGRLIRVKD LPEGWYGAGS
     TDPNFYSDSP LRSVILSMHM GAYGKALDIA RKECPYDVPS NLKPLLTEAG ISQPPPHAPT
     HSHPVHYALR NKYMSLAAKS LQGEWYALFA GPDRINFLRS CGASAPVGAP FSPIYEGKDI
     TRHMGQPIPA VKEPSSPAPV WYVCDALHHL SASTVGSWFD KNPKLEYVVA TTIIPPETLW
     GLPSLCQILY TYSVKNNVLT YVPEGHTGSA YVQPVDGNRW LKTDALITPQ NRCVHVSLLA
     QDYAHQLIVI SRAPLLPQKS RLMCIRNVSI VPWFIHPLGS LYQRLTSPGL NRALQTYITR
     VGSTSIRDIY SKCSAHEVAV FNRYPQSFVR AGALYAKWLR DIDYHTASSG FTYVRWVLTM
     ITRLPIIPFR WYFQSFTSIF SQMNQDEADL WEIQCSTWVS QTSDSLLPGL TAQVCPNKLE
     FFQLQPNADR LSRFAAMSAK LGAWLVLKVL GVISWPLISW CFTHFVSFVD VLFYMLDLHW
     NTSPGGIVFT ILLFWFGVTG PKLSFPNFQF GFIRDFYYGI FVCLYQLPSQ RHVYRVGVNW
     FYCILLNFSL VTLAFPHMHP IIFLLNRTLE HDHYVDGPVN LEPGSFFNIT QVPVDIVHHP
     ISSDIGYNWL RWSCYIVNIL LLAAAYIYAS GLFLEMTTDY EPIHDLEAHN DLSCGSICFH
     HTPSPVVAPA PAVVSTSTAS GSGSSAPVNI VVPPPSPVPS LALPAPAVPI LGNQPLPGTP
     PLAPQVLPAL PAVVANDPLR AYNLPLRILG SFDNWRNLLS RQPVPPNQLD PNNSCVWDVL
     SSHLGIQGSV LWACYVSTLP GWQRARYAQG FVPAEDLSQV LNFFACTYTI YGGIANGICP
     RGPGAQVQPC VFNPAHPPHS VGAGLEGFPT FIAYIQNNQD GSFHFSNRGV ARTGAGAFVP
     PAINDWIGWA SRLVPDVEIG EVVNLPAKGF GTVYRRLLGT MANPLSMFPM GTRLQGYILP
     AVPVRQQIVT YVPNVRDSGY ARALASDFKA KPLALDLTDF SPVDAARTLD QMAKQYDNFV
     RTGSGLQYPQ VRFHLFHGVG GGGKSHTMIQ DLVAQHAVTP FSPHDIMFHA WDHNLRSKFM
     SDVLAAFPQI GLQNNNFTSG CIPLIRPASG TVVFDDAGLM YNSYLPLFMA ANPGVTDIWL
     TFDAAQGQGV IPTANAISRG HPATKDWLSP MSDHYGTEVI RWSQETADLY GFPRRVIPGR
     IAPRGQVVTV SQSPHNVPLL AVSPRFTQTQ SMGGQVANTF QECQGHTING DVCVDLGGLT
     ATCTDTSAWT ALTRPTGHTF LKMGPMMNTS AVVETSWAKS QILTALLTVA TIRSTPYLTA
     AADVDGLVRT AVYSHLARNL SPGACAALGL PAPSPVIGSQ GVKAEYRAGW LNNSKASDYY
     TARTHRAAMG VGGGAGGSAF SRHTAQITND HSPVAHIVRH FTDLDPEAVL HVDSTGYHLP
     EPSPITAQPD PVDDINEPLD DVLREAMIPE NQFETTFQHI VDGAPDALHH TRADKITDIL
     GQRKRIRVGM HSAPWSTTDT KRLRALQKGF RKFFDVASWQ AEGANGPLME QCEREKLASW
     ASKRTKKTLQ QSIDKQDIDM QFTFTRLFPK GQYIKKKAKW RCNAFASQTV SDFHLGRIFR
     DAPRALYLEK QALKYAFDTT YLHCKASPDD MSRWYRQFWQ PGIMTGNDYT AWDSGIDHVF
     LEFDLWLFDI CGFPVEYMER FKFERLNTHS FLGNHMPRQE SGDRWTWILN TLRNVALTGA
     SLDCPPRTPL CVSGDDSVTL GAWRKTVGFN PQEWLMVPKR EEGSTMEFCG LVFGGTDVSF
     GPAVVHWRSR FGLQQGRADA DYWLSIKQAI IETSSKLGCD NTKLAGALLN LRRAILLFNL
     PSHLDIPDAP PEPVHVVETF VCRVNYVLRW FFWLV
//