ID A0A125YTE6_TOXGV Unreviewed; 501 AA.
AC A0A125YTE6; A0A0F7UYR7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ARF1-directed GTPase-activating protein,putative {ECO:0000313|EMBL:CEL75137.1};
DE SubName: Full=Putative GTPase activating protein for adp ribosylation factor {ECO:0000313|EMBL:ESS35971.1};
GN ORFNames=BN1205_020380 {ECO:0000313|EMBL:CEL75137.1}, TGVEG_273070
GN {ECO:0000313|EMBL:ESS35971.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS35971.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS35971.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS35971.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS35971.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS35971.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL75137.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL75137.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
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DR EMBL; LN714498; CEL75137.1; -; Genomic_DNA.
DR EMBL; AAYL02000016; ESS35971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A125YTE6; -.
DR STRING; 432359.A0A125YTE6; -.
DR PaxDb; 5811-TGME49_073070; -.
DR EnsemblProtists; ESS35971; ESS35971; TGVEG_273070.
DR VEuPathDB; ToxoDB:TGVEG_273070; -.
DR eggNOG; KOG0706; Eukaryota.
DR OMA; DDTIFEH; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd08831; ArfGap_ArfGap2_3_like; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 88..201
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..243
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 51897 MW; D223995BB1026B96 CRC64;
MQASFSASAA AQQAPPNASS HPASRAETAF PQTSFSVNAT PSAPLSGVPT PGEAAGAAPG
GSLEGSLARM YMNFPVDAKR YVSEADRDEV FRRLRRENRT CFDCATRNPT WLSVTYGVYL
CLTCSGKHRR LGTHISFVRS CEMDKFYPEQ LLRMEMGGNK RAHEFFREHG MDASKAVDYH
GKLAAKYKQQ LDRVVAHEMQ AAGWVIPSAS PASAEVSPPL SSPVFNAPQT SAPPNPSFSP
AVPAQPLPLS ASSGVPTPGF GPASAVSTAG FSAPAMPQSA SLASEKFGGS AGAGGRVASG
GIRARKLDFD FDFEAEAANA AAVADQKRVE EQMKKAGGFG APASSSAPPS VSGAIAATSV
FPSSFSTPAS VSGIYSPGPA VSPGAPTGGN ASPAPSDPAN SNRFSNAKSI SSEQFFGTSG
STRGSASFQA AINVDPSKRS ISSDEYFGVD STKKQSRLAA FEDQAVVHLD SLKMSAQQGW
ATLASVGSDA VSRARDWLTG S
//
