ID A0A126PJA5_9BACT Unreviewed; 2227 AA.
AC A0A126PJA5;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Peptide synthetase {ECO:0000313|EMBL:AMJ68152.1};
GN ORFNames=AXW84_12020 {ECO:0000313|EMBL:AMJ68152.1};
OS Hymenobacter sp. PAMC 26628.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1484118 {ECO:0000313|EMBL:AMJ68152.1, ECO:0000313|Proteomes:UP000059956};
RN [1] {ECO:0000313|EMBL:AMJ68152.1, ECO:0000313|Proteomes:UP000059956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC26628 {ECO:0000313|EMBL:AMJ68152.1,
RC ECO:0000313|Proteomes:UP000059956};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP014304; AMJ68152.1; -; Genomic_DNA.
DR STRING; 1484118.AXW84_12020; -.
DR KEGG; hyz:AXW84_12020; -.
DR OrthoDB; 4317020at2; -.
DR Proteomes; UP000059956; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000059956};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 514..589
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 605..1029
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1519..1594
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2227 AA; 233453 MW; 5D0EA320DE7BD312 CRC64;
MGALVHTPRL VHHLFEQAAS AHAGRTAVVF GADSLTYQQL NDRADRLCQS VLHHAPAAEF
VGISTTRGLD MVVGVLAILK AGKAYLPLDP TYPEQRLQQL VGSARLEICL APAAETTLFA
GLGLRMLAGE GAPPSSRPPS PAGELAYVLF TSGSTGTPKG VCMGHRPLVN LLQWQQRRSA
ATAGTRTLQF APLGFDVSFQ EIMATLSTGG TLVLVADNLR LDFARLLAFI AQQAINRLFL
PFVALQYLAE VAVNTQQFPA GLAEVMTAGE QLKITPQIAA FFAALPGCVL FNQYGPTESH
VVTELALTGD PAAWPALPTI GRPIDNVDVF IVDEALALVP AGAVGELCIS GACLAAGYLH
QPTLTDEKFV QWHAPTGDPA RLYRTGDLAR WLPDGNVEFL GRRDDQVKIR GHRVELGEVE
AALNAVPGVK QAVVVARDAD TGSRRLVAYL VAGSAPPDVT ELYQILGKTL PDYMLPAAFV
WLDDLPKTTS GKVDKRALPA PATHRPALAT VYHRAGTALE KAVAGVWAEV LGLDRVGLDD
NFFELGGNSL LAQKTVALLE HRCAHRLPIT KLYQFPTVGG TARYLAPPAT TPRPAAPILG
PKAATGDVAV VGLAGRFPGA PTVGALWDVL REGRETTSFF SPDELDASIP AAVKNDPLYV
PARGIIAGAD QFDAGFFGLT PKLAEAMDPQ QRLFLEIAWE ALEQTGHLPA HYAGRVGVFA
GCGHNTYFLH NVLGNPAASQ VGSFQVMLAN EKDYIATRTA YQLDLKGPAV SVHSACSTSL
LAIAQAVQSI RSGQCEVALA GGASITAPVR SGHVYQEGSM MSADGHCRPF DADARGTVFS
DGAGVVVLKD AAAARRDGDT IYAVIKGVGV NNDGGGKGSF TAPNADGQAG AIRMALADAG
VAPATLSYVE AHGTATPVGD PIEMEGLLSA FGAQAERQFC ALGSIKSNMG HLTAAAGVAG
FIKTALALHH RQIPASLGYA APNPLIDFVN SPFFVNTALA DWPAGGGPRR AGVSSFGVGG
TNVHVIVEEA GAPAGAPGAP APARPAELVV WSAKSAASRE AYAQRLADAL NAPDAPALAD
VAFTLPTTRA PFAHRRFAIA ADGPELRAQL QAPAAAGTAG ALAGAPGDLF FLFPGQGAQY
VGMGRELYDH EPAYRAAVDE CASLLGPHLP TDLRAVLFAG PGDAAADARL RDTRYAQPAL
FVTEYALARL WASWGVVPTG YCGHSVGEFV AAHLAGVFSL VDALALVATR GRLVGELPGG
SMLSVRLAAG QLADLLPAGL SVAAVNGPAA AVVAGPAEDV AAFARTLDAQ DVPNRALATS
HAFHSAMMDP AVDAFRQAVA NVSLHHPQKP VVSTVSGTWL TDAQATDPDY WAAHLRQTVQ
FAPALDTLLT ESQPILLEVG PGHVLAALAQ QQLAGRPATV LASLKKGPGP HPEYRALLGA
LGQLWLRGVA PDWAALHAER RPRRVLLPTY AFDRKPCWLA PAAAVPASIL PPPAPAPPAA
SAAGAPVPFT PPVIPMRKSV LLTTLSEVLE NASGIEMAGV SPDLTFLEIG FDSLLITQLA
LALKKQFGLP ITFRQLNENY ATPNQLADYL DQALPPAAYQ PTAATPTPAP APTAYEAPAP
QPVPVAPAPV AFAPLAGPGN DSALGLIAQQ LQILAKQMAL LQGAAPATAL APLPAPALAA
PALAPASAHG SAPTAGAPAA APQITAEEAV EIKKPFGASP RIEKHASQLT ERQQAFLRDL
TARYTQKTKA SKAYTQQHRS RMADPRVVSG FRPLTKELVY PLVVDRSKAS KLWDLDGNEY
LDVLNGFGSC IFGHQPPFIA EALHAQIERG YEVGPQHALA GEVCDLLCEF TGTDRVALCS
TGSEAVLGGM RIARTVTGRS LIVAFSGSYH GIVDEVLVRG TKALKSFPAA AGIMPESVQN
MLILDYGTDE SLRIITERAS ELAAVLVEPV QSRRPEFQPV EFLHQLRTVT AAAGTVLIFD
EVITGFRLHP GGAQALFGVQ ADLATYGKVV GGGLPIGVIA GKRALMDALD GGAWQFGDDS
VPEIGVTYFA GTFVRHPLAL AAARASLLHL KAQGPAFQQG LTAKTERLAG LLNQSFAQQQ
LPFFVAQFGS LWKIKFREEI PYSELMFTLL REKGLHIWDG FPCFMTEAHT DADVDLIADL
LLAGVREMLE AGFFQAAPVA GHVVPAALSP APALNQPPVP GARLGRDRNG NPGWFVANGS
TGDYVKV
//
