ID A0A126T6C0_9GAMM Unreviewed; 1253 AA.
AC A0A126T6C0;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=JT25_014290 {ECO:0000313|EMBL:AMK77633.1};
OS Methylomonas denitrificans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=1538553 {ECO:0000313|EMBL:AMK77633.1, ECO:0000313|Proteomes:UP000030512};
RN [1] {ECO:0000313|EMBL:AMK77633.1, ECO:0000313|Proteomes:UP000030512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJG1 {ECO:0000313|EMBL:AMK77633.1,
RC ECO:0000313|Proteomes:UP000030512};
RX PubMed=25580993; DOI=10.1111/1462-2920.12772;
RA Kits K.D., Klotz M.G., Stein L.Y.;
RT "Methane oxidation coupled to nitrate reduction under hypoxia by the
RT Gammaproteobacterium Methylomonas denitrificans, sp. nov. type strain
RT FJG1.";
RL Environ. Microbiol. 17:3219-3232(2015).
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DR EMBL; CP014476; AMK77633.1; -; Genomic_DNA.
DR RefSeq; WP_062328934.1; NZ_CP014476.1.
DR AlphaFoldDB; A0A126T6C0; -.
DR STRING; 1538553.JT25_014290; -.
DR KEGG; mdn:JT25_014290; -.
DR OrthoDB; 5571542at2; -.
DR Proteomes; UP000030512; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030512}.
FT DOMAIN 343..395
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 400..455
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 474..527
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 689..736
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 763..815
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 847..980
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 989..1243
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1253 AA; 138714 MW; F41FDB1B3BB16C2B CRC64;
MRSSIGIKLG FWLALLGTLS TGLTGYYVYD RSRVMLVETA KDKLLNDTQG LGHRFADALA
ATASNVKLLA NLPLSTDIAS AKPNTELPIR KNQLAEIFVS LLNAHPEYSQ IRLIDTRHYG
KELVRVDRDR DTLKVIAEAQ LQEKNHFPYV FETVPLPADQ YYVSEINLNQ ELGAHQGFGK
PTLRVAMPIK STNFTIAVVV INVDLDGLFE QVRSNISDDI KLLLSNDRGD YLIHPDDAKT
FGFESGRSFL IQDDIPDIKA ILAGKQQHSA FATSDTQSLA ASSLAAFVKL PLGSASSGRF
VMLGLYTPLQ NVLVESKALG VGVIEITLLF SLLASAISLL LARVLAKPLN SMTTAIGQFK
LGAPLTGLPT HRNDEIGYLA NSFMSMTEQL NSQIAELHAS EAKLHAILDN APVGIWLADL
DRHFLFVNQT FCDALGLPEA RFIANEQLAE LFGAEIAARF LTADQECLAQ ADQPHQSLEQ
IKFADGKRHT IQITRTQLQD INKETVGIIG IAMDISDRQQ AANRERAHNH VLELLSKGAA
LPEILQAVVL GVETQNPDLL CSILLLNSEG NRLFIGAAPR LPDFYNAAVD GLYIGPGVGS
CGTAAYFGQR VIVEDIQNHT YWGPFTELAA QAGLGACWSE PIRGASGRLL GTFAIYQRHP
AAPGAEDIQM IEQASHLAGI AIDRSRSNEE LQLASLVYQN SSEAMAVTDA QGMIINVNPA
FTELTGYALD EVIGKNHNIL NSQRQGEQFY QAMWQAINSS GYWKGEIWNR RKNGEIFAEQ
LTINTIFSVD GLPQRRVALF SDITQKKQSE ELIWNQANFD PLTGLPNRRM FHDRLDQEIK
KAHRSGLQVA LILLDLDRFK EVNDTLGHDM GDLLLKDASQ RLLRCVRDSD TVARLGGDEF
TVILGELEDA DNVERVVNNI LQRLVEPFQL KTKVAYISAS IGITLYPKDA ERIDALIKNA
DQAMYAAKHQ GRNRYCYFTP SMQEAAQARM LIAEDLRNAL ETNQFEVYYQ PVVELGSGAI
HKAEALIRWQ HPTRGTVSPA EFVHIAEDIG LIAEIGDWVF KQAASQVKQW RKRYHPDFQI
SVNKSPVQFY DGHSRDTWLE HLQTLELPGQ SIVAEITEGL LLDASNVVKD QLLAFRDAGI
QVSLDDFGTG YSSLAYLKKF DIDYLKIDQS FVGNLSPNSS DKVLCEAIIV MAHKLGMKVI
AEGIETEQQR ELLLESGCDY GQGYLFSKPL SAMKFEELLI RHGTSKSTAS DLI
//
