ID A0A126T7D1_9GAMM Unreviewed; 490 AA.
AC A0A126T7D1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:AMK77940.1};
GN ORFNames=JT25_015885 {ECO:0000313|EMBL:AMK77940.1};
OS Methylomonas denitrificans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=1538553 {ECO:0000313|EMBL:AMK77940.1, ECO:0000313|Proteomes:UP000030512};
RN [1] {ECO:0000313|EMBL:AMK77940.1, ECO:0000313|Proteomes:UP000030512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJG1 {ECO:0000313|EMBL:AMK77940.1,
RC ECO:0000313|Proteomes:UP000030512};
RX PubMed=25580993; DOI=10.1111/1462-2920.12772;
RA Kits K.D., Klotz M.G., Stein L.Y.;
RT "Methane oxidation coupled to nitrate reduction under hypoxia by the
RT Gammaproteobacterium Methylomonas denitrificans, sp. nov. type strain
RT FJG1.";
RL Environ. Microbiol. 17:3219-3232(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP014476; AMK77940.1; -; Genomic_DNA.
DR RefSeq; WP_036275800.1; NZ_CP014476.1.
DR AlphaFoldDB; A0A126T7D1; -.
DR STRING; 1538553.JT25_015885; -.
DR KEGG; mdn:JT25_015885; -.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000030512; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029095; NarX-like_N.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF3; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13675; PilJ; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030512};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..264
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 355..488
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 490 AA; 54023 MW; FA10570D2E4FCAFE CRC64;
MTENARGRIP AVFIPVLLFI VFDAVALGLN FWISARLEEN AVAINLSGRQ RMLSQRMTKA
LLMLHVAQTD TEKLSAFTEF SNAVGLFDKT LSGFLQGGIT SSGDGKPVYL SATEAVNTQV
ITGSASLLWT LIHKRLLPVE MGGAQVGAEV LLPALNTLLT HNTQLLGLMN DLTTALELNA
TKEVIYLRTL QASLLLLALL NFALVCKRLL AQIKQSQGNV QALRNIIDSI ETGIVLYGRD
ECVRSANKTA NQLFGYSDQA LIGKPLNQLI VADNARILGL RRDNSTFVAK INIQTLFEFN
DQISLCTITD VSEQERKEKQ LMYLAFHDQL TGLPNRGLLI ERLRQDLLRA KRDSTFLAVF
FLDLDGFKVV NDEMGHDAGD ELLQAVARRF EQCCREVDTV ARLGGDEFVF VLTSLHSVLA
AKQVAQNVLK AINQAFLIHG KTVKIGASIG IAMYPTDHSE AELLIKCADD AMYLAKQRGK
NQLAFTVECR
//
