ID A0A126Z0G9_9MICO Unreviewed; 161 AA.
AC A0A126Z0G9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Transcriptional repressor NrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN Name=nrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN ORFNames=AX769_12020 {ECO:0000313|EMBL:AMM20733.1};
OS Frondihabitans sp. PAMC 28766.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Frondihabitans.
OX NCBI_TaxID=1795630 {ECO:0000313|EMBL:AMM20733.1, ECO:0000313|Proteomes:UP000070552};
RN [1] {ECO:0000313|EMBL:AMM20733.1, ECO:0000313|Proteomes:UP000070552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC28744 {ECO:0000313|Proteomes:UP000070552};
RA Park H.;
RT "Complete genome of Frondihabitans sp.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes. {ECO:0000256|HAMAP-Rule:MF_00440}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00440};
CC Note=Binds 1 zinc ion. {ECO:0000256|HAMAP-Rule:MF_00440};
CC -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000256|HAMAP-
CC Rule:MF_00440}.
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DR EMBL; CP014513; AMM20733.1; -; Genomic_DNA.
DR RefSeq; WP_066279591.1; NZ_CP014513.1.
DR AlphaFoldDB; A0A126Z0G9; -.
DR STRING; 1795630.AX769_12020; -.
DR KEGG; frp:AX769_12020; -.
DR OrthoDB; 9807461at2; -.
DR Proteomes; UP000070552; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00440; NrdR; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003796; RNR_NrdR-like.
DR NCBIfam; TIGR00244; transcriptional regulator NrdR; 1.
DR PANTHER; PTHR30455; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR PANTHER; PTHR30455:SF2; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Metal-binding {ECO:0000256|HAMAP-Rule:MF_00440};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Reference proteome {ECO:0000313|Proteomes:UP000070552};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|HAMAP-Rule:MF_00440};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00440}; Zinc {ECO:0000256|HAMAP-Rule:MF_00440};
KW Zinc-finger {ECO:0000256|HAMAP-Rule:MF_00440}.
FT DOMAIN 46..136
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT ZN_FING 3..34
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00440"
SQ SEQUENCE 161 AA; 17724 MW; 7F6B7A257F22CC1D CRC64;
MFCPFCRHPD SRVVDSRTSD DGTSIRRRRQ CPNCGRRFST TETASLAVIK RNGVLEPFSR
EKIISGVRKA CQGRPVTDGD LAVLAQKVEE AVRASGASQI DANEVGLAIL PPLRELDEVA
YLRFASVYQA FESLDDFEDS IRQLRAEHAG KPAREASAAA E
//
