ID A0A126ZFI0_9BURK Unreviewed; 394 AA.
AC A0A126ZFI0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AMM25873.1};
GN ORFNames=AX767_17060 {ECO:0000313|EMBL:AMM25873.1};
OS Variovorax sp. PAMC 28711.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1795631 {ECO:0000313|EMBL:AMM25873.1, ECO:0000313|Proteomes:UP000070169};
RN [1] {ECO:0000313|EMBL:AMM25873.1, ECO:0000313|Proteomes:UP000070169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 28711 {ECO:0000313|EMBL:AMM25873.1,
RC ECO:0000313|Proteomes:UP000070169};
RA Park H.;
RT "Complete genome of Variovorax sp.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP014517; AMM25873.1; -; Genomic_DNA.
DR RefSeq; WP_068632413.1; NZ_CP014517.1.
DR AlphaFoldDB; A0A126ZFI0; -.
DR STRING; 1795631.AX767_17060; -.
DR KEGG; vaa:AX767_17060; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000070169; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000070169};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AMM25873.1}.
FT DOMAIN 6..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..393
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 350
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 380
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 394 AA; 40898 MW; 6C34C6493E063D5D CRC64;
MTSRDIFVVG TARTAIGTFG GSLKDVPNTQ LATTAVKAAL ERSGVAPDAI GHVVMGNVIP
TDVKDAYLSR VAAIDAGCPI ETPAFNVNRL CGSGLQAIVS AAQAIALGDC DIAIGGGSES
MSRGPYFDTA ARYGARMGDA VLVDYMLGIL HDPWEKMHMG ITAENVAARY GITREQQDQL
AVMSQQRAAA AITAGRFKEQ IVSVEVKTRK GVVLFDTDEH VRADTTMEAL AKMKPAFKKD
GLVTAGNASG INDGAAAVVL AEGSRVQVLG LKPLARLVGY AHAGVEPAYM GIGPVPATRK
VLARTGLKVS DLDVIESNEA FAAQACAVIK ELDFDPARVN PNGSGISLGH PVGATGAIIT
TKAIAELHRI GGRYALVTMC IGGGQGIAAI FERV
//
