ID A0A127A007_9MICC Unreviewed; 362 AA.
AC A0A127A007;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN ORFNames=SA2016_1514 {ECO:0000313|EMBL:AMM32191.1};
OS Sinomonas atrocyanea.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Sinomonas.
OX NCBI_TaxID=37927 {ECO:0000313|EMBL:AMM32191.1, ECO:0000313|Proteomes:UP000070134};
RN [1] {ECO:0000313|EMBL:AMM32191.1, ECO:0000313|Proteomes:UP000070134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 3377 {ECO:0000313|EMBL:AMM32191.1,
RC ECO:0000313|Proteomes:UP000070134};
RA Kim K.M.;
RT "Complete genome of Sinomonas atrocyanea KCTC 3377.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; CP014518; AMM32191.1; -; Genomic_DNA.
DR RefSeq; WP_066497030.1; NZ_CP014518.1.
DR AlphaFoldDB; A0A127A007; -.
DR STRING; 37927.SA2016_1514; -.
DR KEGG; satk:SA2016_1514; -.
DR PATRIC; fig|37927.3.peg.1562; -.
DR OrthoDB; 9815856at2; -.
DR Proteomes; UP000070134; Chromosome.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AMM32191.1};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000070134};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AMM32191.1}.
FT DOMAIN 96..309
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 362 AA; 36710 MW; CE4D717A7C41AAA3 CRC64;
MEITVSLEGL PVVVLGDADE SRQALARYRA AGARLTFFSS AEAYMAAAAV PARPALVAVV
GRPEAHDAAW APVLDHYRRL GVPLVAEPPA GRRGHVTLVG GGPGSRGLLT VEAVEALRDA
DIVLFDRLAP WRELPALTTA RLVDVGKLPG HHKVPQEEIN RLLVDYATYG LTGRPANVVR
LKGGDPFVFG RGAEEAAACA AAGVPVRVVS GISSSIAVPA AAGIPVTHRN VSHSFTVISG
HAPLTDAEHR HLAGLAAEGG TVVVLMGIAT LPHLAAGLRR AGLGLATPLA VVERGHQAGQ
RTTVTALGSA EADTAGCGNP AVIVIGDVVR AAGHGAAGGG AYADELRGLV GALAEQPAGS
AA
//
