ID A0A127JWF1_9BURK Unreviewed; 351 AA.
AC A0A127JWF1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:AMO24244.1};
GN ORFNames=UC35_17120 {ECO:0000313|EMBL:AMO24244.1};
OS Ramlibacter tataouinensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Ramlibacter.
OX NCBI_TaxID=94132 {ECO:0000313|EMBL:AMO24244.1, ECO:0000313|Proteomes:UP000070433};
RN [1] {ECO:0000313|EMBL:AMO24244.1, ECO:0000313|Proteomes:UP000070433}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-10 {ECO:0000313|EMBL:AMO24244.1,
RC ECO:0000313|Proteomes:UP000070433};
RX PubMed=24425747; DOI=10.1099/ijs.0.058396-0;
RA Lee H.J., Lee S.H., Lee S.S., Lee J.S., Kim Y., Kim S.C., Jeon C.O.;
RT "Ramlibacter solisilvae sp. nov., isolated from forest soil, and emended
RT description of the genus Ramlibacter.";
RL Int. J. Syst. Evol. Microbiol. 64:1317-1322(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP010951; AMO24244.1; -; Genomic_DNA.
DR RefSeq; WP_061501796.1; NZ_CP010951.1.
DR AlphaFoldDB; A0A127JWF1; -.
DR PATRIC; fig|94132.3.peg.3498; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000070433; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000070433}.
FT DOMAIN 256..350
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 220..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 39587 MW; 8BF6F3AE6468BEBC CRC64;
MSLIPATIVT GFLGSGKTTL LKRVLTEAHG QKIAVIENEF GEENIDSDIL VTDTQEQIIQ
MSNGCICCTI REDLRSTLQL LAAKRRKGLL DFERVVIETT GLADPGPVAQ TFFMDDEIAE
SYLLDSIITL VDAKHSAQQL NDRQEARRQV GFADRIFISK ADLVSQEEVD ALVHRLKHMN
PRAPQRAVHF GEVSLPEVFD LRGFNLNAKL DIDPDFLKEE EDDHHDHNHD HEHGEHCDHP
SHAHGHGHHH HHDDDVKSFV FKSERAFDPA KLEDFLGAVV NIYGPRMLRY KGVLHMKGTD
RKVIFQGVHQ LMGSDLGPQW AEGEARGNKM VFIGIDLPRE IFLQGLEQCL I
//
