ID A0A127R4C7_9BURK Unreviewed; 340 AA.
AC A0A127R4C7;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000256|HAMAP-Rule:MF_00081};
GN Name=hrcA {ECO:0000256|HAMAP-Rule:MF_00081,
GN ECO:0000313|EMBL:AMP16847.1};
GN ORFNames=CPter291_4627 {ECO:0000313|EMBL:AMP16847.1}, CPter91_4813
GN {ECO:0000313|EMBL:AMP07108.1};
OS Collimonas pratensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Collimonas.
OX NCBI_TaxID=279113 {ECO:0000313|EMBL:AMP16847.1, ECO:0000313|Proteomes:UP000074914};
RN [1] {ECO:0000313|Proteomes:UP000074561, ECO:0000313|Proteomes:UP000074914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ter291 {ECO:0000313|EMBL:AMP16847.1,
RC ECO:0000313|Proteomes:UP000074914}, and Ter91
RC {ECO:0000313|EMBL:AMP07108.1, ECO:0000313|Proteomes:UP000074561};
RA Song C., Schmidt R., de Jager V., Krzyzanowska D., Jongedijk E., Cankar K.,
RA Beekwilder J., van Veen A., de Boer W., van Veen J.A., Garbeva P.;
RT "Exploring the genomic traits of fungus-feeding bacterial genus
RT Collimonas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-
CC dnaJ and groELS operons). Prevents heat-shock induction of these
CC operons. {ECO:0000256|HAMAP-Rule:MF_00081}.
CC -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000256|HAMAP-
CC Rule:MF_00081}.
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DR EMBL; CP013234; AMP07108.1; -; Genomic_DNA.
DR EMBL; CP013236; AMP16847.1; -; Genomic_DNA.
DR RefSeq; WP_061944255.1; NZ_CP013236.1.
DR AlphaFoldDB; A0A127R4C7; -.
DR STRING; 279113.CPter91_4813; -.
DR KEGG; cpra:CPter91_4813; -.
DR PATRIC; fig|279113.10.peg.4607; -.
DR OrthoDB; 9783139at2; -.
DR Proteomes; UP000074561; Chromosome.
DR Proteomes; UP000074914; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00081; HrcA; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR002571; HrcA.
DR InterPro; IPR021153; HrcA_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR005104; WHTH_HrcA_DNA-bd.
DR InterPro; IPR023120; WHTH_transcript_rep_HrcA_IDD.
DR NCBIfam; TIGR00331; hrcA; 1.
DR PANTHER; PTHR34824; HEAT-INDUCIBLE TRANSCRIPTION REPRESSOR HRCA; 1.
DR PANTHER; PTHR34824:SF1; HEAT-INDUCIBLE TRANSCRIPTION REPRESSOR HRCA; 1.
DR Pfam; PF01628; HrcA; 1.
DR Pfam; PF03444; HrcA_DNA-bdg; 1.
DR PIRSF; PIRSF005485; HrcA; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|HAMAP-Rule:MF_00081};
KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP-
KW Rule:MF_00081};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00081};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00081}.
FT DOMAIN 5..74
FT /note="Winged helix-turn-helix transcription repressor HrcA
FT DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF03444"
FT DOMAIN 105..323
FT /note="Heat-inducible transcription repressor HrcA C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01628"
SQ SEQUENCE 340 AA; 37247 MW; 1003614A748647C9 CRC64;
MQLDNRAQTL LKALVERYIA DGQPVGSRAL SKISGLELSP ATIRNIMADL EEMGFVASPH
TSAGRVPTPR GYRMFVDTLL TVEAIDETAL ESKMQNSLQP SSQQKIIANA AQVLSSLSHF
AGVVLSPRRE SIFQQIEFLR LSEKRILLVI VSPNGDVQNR LLLTDVDYSP AKLVQAANYI
NQHYGGLSLD DVRLRLQGEL RKLRDDMTWL MQAAVEAGSD AMTDNSDEVV ISGERNLLSV
TDLSSNMDSL RKLFDMFEQK TGLMQLLDIS GKATGVQIFI GGESQLVPMD EMSVVTAPYE
VNGKIVGTLG VIGPTRMAYE RVIPIVNITA KLLSNALSHS
//
