ID A0A127V838_9SPHI Unreviewed; 1436 AA.
AC A0A127V838;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:AMP97138.1};
GN ORFNames=AY601_0167 {ECO:0000313|EMBL:AMP97138.1};
OS Pedobacter cryoconitis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=188932 {ECO:0000313|EMBL:AMP97138.1, ECO:0000313|Proteomes:UP000071561};
RN [1] {ECO:0000313|EMBL:AMP97138.1, ECO:0000313|Proteomes:UP000071561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27485 {ECO:0000313|EMBL:AMP97138.1,
RC ECO:0000313|Proteomes:UP000071561};
RA Lee J., Kim O.-S.;
RT "Complete genome sequence of Pedobacter cryoconitis PAMC 27485.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014504; AMP97138.1; -; Genomic_DNA.
DR RefSeq; WP_068395264.1; NZ_CP014504.1.
DR KEGG; pcm:AY601_0167; -.
DR PATRIC; fig|188932.3.peg.170; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000071561; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0008897; F:holo-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.90.470.20; 4'-phosphopantetheinyl transferase domain; 2.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR008278; 4-PPantetheinyl_Trfase_dom.
DR InterPro; IPR037143; 4-PPantetheinyl_Trfase_dom_sf.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43074; OMEGA-3 POLYUNSATURATED FATTY ACID SYNTHASE PFAB-RELATED; 1.
DR PANTHER; PTHR43074:SF1; PKS_AT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01648; ACPS; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF56214; 4'-phosphopantetheinyl transferase; 2.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000071561};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 3..457
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 1436 AA; 157968 MW; 7E7479AE877E66DE CRC64;
MKKTDVAVIG MSCIFPGAGD LDTFWKNIIN KVDSTQVVPP DRIDPVHFDK DSTGVDRFYC
NRGGFIPDYN FDPQRFGILP VAVNGTEPDH LLTLDLVYSS LEDAGVFEKN TSLAKTGIII
GKGNYAGPGA TRAIEIVRTG EQIAAVLKDL LPQLETAAIE KVKHEFQARK GRFGPDTAMG
LIPNLVASLV ANRLNLGGVA FTLDAACASS LIAIDHAIQE LNSGRCNMVI AGGVHVGQNA
AFWSIFSNLG ALSKQEKIKP FDAGADGLII GEGCGFVVLK RLEDAIQDKD RIYAVLKGAG
VSSDGSGTSV MSPSVKGQLR AITQAWENSG LSAKDIGYIE AHGTGTPLGD KTELETLTQF
FGHDAELPKA GIGTVKSNIG HAMPAAGIAG LIKTCLALYH DILPPTLHCE NPLTQLAKTQ
FSAVQEPLSW EKSGLPKIAG VNAFGFGGIN AHVVLEGFNA PKKDKVLLLA RPTHEELIHA
LENNDYSAGN GNYRIALFDP TPERIKKAIK IAAKNNPWRN KQDIWYTNEP LISNGGKIAF
VFPGLDGLAG GEVSSVTDYF NIAEAQHAKA EGLLSDALKT LNKSSVLDIA LKQLGVQPDM
NAGHSLGEWL AARSSELAEE SSVSQLLKVL DPETFELKDS RFIAVGCGIE LLLPIIANIN
DVYLSNDNCP QQVILCGSKN ALEELTPLLK ARQIFHQILP FQSGFHSPFI ADKLEVILEG
MKDMQFRKTT TPLWSATTLE LYPEGFEAIR QLSAEHLIKP VRFRELTAKL YEQGARVFIQ
IGSGGLVGFI DDTLKGKNFS TISSNVPVRS GITQLQRVIA ALFVEGKETG LDFLGQIKSS
PASKGKGIKL ELGLPTITGL NSLKELAAGS PSVHAQPNPA VYAKGLLEDV ADPVMEAFNE
NILEMANIQA EIQQLFKDRV LQPANYTNRL TKPEFATPEV STPLAPQVLA TPLNRMPFSK
QLDITLENCP YLKDHALLRQ PKDWHCVDDM DPVIPMTMIF ELFGEIAEEQ SRGEQVHKIL
NIKVFQWMNV VKPFRETITG EWKDQQKVYL NLERFANAEV LLAEKLGIPP AQQSFDIGKI
LDIQRTAEQI YENHMFHGPG YQGIKHLKAV GEKGITGTIE SGAGKGSLLD NAGQLFGLWL
QLILTKDRIA FPVKIQEIEF FGNMHDQQGE FECTCVLTDM NEEFATGNFI IKRDHQVWAI
ISGWQNRRLE IDDALWSVSM SPLHNRLSKE IAPGIFMFHN AYSRVVSWDF ILKRYFNQDE
KKYHNALLPN KRKTWMISRV AVKDAVRDLL NKEKQHACYP ITFEIKSDEL QKPYPHGGQT
AGIHVSLAHK GTDAVGIARL NRPVGIDIES IEERSAGFFD LAFTSTEMAL LQGRDKAEWA
TRFWTAKEAY GKYLGKGLQG NPKAYGVEEI IGEELRIKDT IIKTIKHHNY IIGWTQ
//
