ID A0A127V9P4_9SPHI Unreviewed; 233 AA.
AC A0A127V9P4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=AY601_1146 {ECO:0000313|EMBL:AMP98073.1};
OS Pedobacter cryoconitis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=188932 {ECO:0000313|EMBL:AMP98073.1, ECO:0000313|Proteomes:UP000071561};
RN [1] {ECO:0000313|EMBL:AMP98073.1, ECO:0000313|Proteomes:UP000071561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27485 {ECO:0000313|EMBL:AMP98073.1,
RC ECO:0000313|Proteomes:UP000071561};
RA Lee J., Kim O.-S.;
RT "Complete genome sequence of Pedobacter cryoconitis PAMC 27485.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP014504; AMP98073.1; -; Genomic_DNA.
DR RefSeq; WP_068397698.1; NZ_CP014504.1.
DR AlphaFoldDB; A0A127V9P4; -.
DR KEGG; pcm:AY601_1146; -.
DR PATRIC; fig|188932.3.peg.1183; -.
DR Proteomes; UP000071561; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000071561};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000313|EMBL:AMP98073.1}.
FT DOMAIN 27..223
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 233 AA; 25410 MW; A5CB869D8A863B94 CRC64;
MKRILMILTS HQQMENTDSK TGVWLGEFTD PYYEFIDQGY QVTLASPLGG KPPVDTMSEL
TEHVTGANRR FTDDEFAQSA FKHTHTLVGL SATDFDAVFF PGGHGPIWDL ANDELSAKLI
LEFFDLDKPV AAVCHGPAAL IKAAELSPGL LAGKKLTSFT NTEEKLVGRS ANIPYKLEDK
LIELGADFKS ALLPFLVNVE TDGLLITGQN PLSAGPVAKA LIEVLEKEIE SEF
//
