ID A0A128A0T6_9ARCH Unreviewed; 554 AA.
AC A0A128A0T6;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=NDEV_0196 {ECO:0000313|EMBL:CUR50961.1};
OS Candidatus Nitrosotalea devanaterra.
OC Archaea; Nitrososphaerota; Nitrosotalea.
OX NCBI_TaxID=1078905 {ECO:0000313|EMBL:CUR50961.1, ECO:0000313|Proteomes:UP000196239};
RN [1] {ECO:0000313|Proteomes:UP000196239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lehtovirta-Morley L.E., Vieille C.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN890280; CUR50961.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A128A0T6; -.
DR KEGG; ndv:NDEV_0196; -.
DR Proteomes; UP000196239; Chromosome 1.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034471; GDGT/MA_synthase.
DR InterPro; IPR034474; Methyltransferase_Class_D.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43306; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43306:SF1; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00385; 7_8-dihydro-6-hydroxymethylpte; 1.
DR SFLD; SFLDG01100; methyltransferase_(Class_D); 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 104..321
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 554 AA; 63353 MW; EDD344F426EE1717 CRC64;
MELIQISNQK TPTLGKKSTI RFTQSICPEC NMILDAEVFE RDGKVFMTKT CPTHGECEEL
YFGSYDMYKK FSTYWIDGKG AHAPNVMIDK CSCPNNCGLC SNHLSHSGLA NMIVTNRCDL
TCWYCFFYVK KGLEGAYMYE PSQDQVRAMM KTLRAERPIP GNSMQITGGE PMLREDIVDV
IKIMKEEGVD HIQMNTNGIR FALDPEAMRE VRLAGVNNLY LSFDGVTPRT NPKNHWEIPY
ALESARKTGT TVVFVPTVIK SINDHELGPI IRYAQKNMDV VHAVNFQPVS LTGRMGKKER
EKYRITIPDC IQRIEEQTQG EVTVDDWFPV PSCMPLTNVI EAFSSKPKYE LSIHFACGAG
TYIFEDAETK KFVPLTRFAD IQGMLELFED KAEEIKSGKN KYFTMLEVVR KLSSFIDKKK
QPAGLDLAKM FGSILMKRSF NSVGSWHVKG LFLGMMHFQD KYNEDLERLQ RCDIHYLTPD
LRIVPFCAFN VIPEWYRDRI QKKYSISVEE WEKRVGVKLE DGLYRGIMRR GSGDELAAGC
AKSQMMHEAS QSLM
//
