ID A0A128A3C9_9ARCH Unreviewed; 408 AA.
AC A0A128A3C9;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=threonine ammonia-lyase {ECO:0000256|ARBA:ARBA00012096};
DE EC=4.3.1.19 {ECO:0000256|ARBA:ARBA00012096};
GN Name=ilvA {ECO:0000313|EMBL:CUR51851.1};
GN ORFNames=NDEV_1086 {ECO:0000313|EMBL:CUR51851.1};
OS Candidatus Nitrosotalea devanaterra.
OC Archaea; Nitrososphaerota; Nitrosotalea.
OX NCBI_TaxID=1078905 {ECO:0000313|EMBL:CUR51851.1, ECO:0000313|Proteomes:UP000196239};
RN [1] {ECO:0000313|Proteomes:UP000196239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lehtovirta-Morley L.E., Vieille C.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-
CC oxobutanoate from L-threonine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00004810}.
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DR EMBL; LN890280; CUR51851.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A128A3C9; -.
DR KEGG; ndv:NDEV_1086; -.
DR UniPathway; UPA00047; UER00054.
DR Proteomes; UP000196239; Chromosome 1.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Isoleucine biosynthesis {ECO:0000256|ARBA:ARBA00022624};
KW Lyase {ECO:0000313|EMBL:CUR51851.1}.
FT DOMAIN 333..408
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 408 AA; 43402 MW; 4AB6A73691620BA9 CRC64;
MGLKTLLNVT FDDIVKSQKI QRNVIRRTPL ESSHSFSVMT GSKVYLKSEC LQKTGSFKFR
GAYAKIASLS KAEKKKGVIA ASAGNHAQGV AYASSLEKIP CTIVMPVTAS PAKVSATRSY
GANVILEGAI YDESSARAAD IAQKTGATMV HAFDDETVIA AQGVIGLEIM EDLPDVDEIY
VPIGGGGLAA GILKAVKTKK PKVKVIGVQS SGFPAMKKSF DLGKLQSVSG HRTIADGISV
KTPGHSTFKI INELIDDIVL VDDSSIVKAM FLLMERSKTV VEPAGAVGLA YLLDKKPAKG
KKVVSILSGG NVDMYLLGQI VAKGLTEMGR MVKIFILLTD KPGALKEVID QISSLSVNIV
DVIHDRLSSS IPAGTAGVTL SLETQDSDHA EQLIRFLKKK NVQFKVVT
//
