ID A0A131ZTG8_SARSC Unreviewed; 881 AA.
AC A0A131ZTG8;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=QR98_0002420 {ECO:0000313|EMBL:KPL97158.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPL97158.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPL97158.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPL97158.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPL97158.1}.
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DR EMBL; JXLN01000226; KPL97158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A131ZTG8; -.
DR VEuPathDB; VectorBase:SSCA004102; -.
DR OMA; FTGQTCG; -.
DR OrthoDB; 5473534at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 10.
DR Gene3D; 2.10.25.10; Laminin; 16.
DR InterPro; IPR006149; EB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24033:SF151; PROTEIN EYES SHUT; 1.
DR Pfam; PF01683; EB; 1.
DR Pfam; PF00008; EGF; 8.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF12661; hEGF; 2.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00181; EGF; 17.
DR SMART; SM00179; EGF_CA; 14.
DR SUPFAM; SSF57196; EGF/Laminin; 10.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 11.
DR PROSITE; PS00022; EGF_1; 16.
DR PROSITE; PS01186; EGF_2; 14.
DR PROSITE; PS50026; EGF_3; 18.
DR PROSITE; PS01187; EGF_CA; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 62..96
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 98..137
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 144..181
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 183..219
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 221..259
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 261..297
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 299..334
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 336..372
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 374..410
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 412..448
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 450..486
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 488..524
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 526..563
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 565..602
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 604..661
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 663..699
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 701..730
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 773..812
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 86..95
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 108..125
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 127..136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 171..180
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 209..218
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 230..247
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 249..258
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 287..296
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 303..313
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 324..333
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 362..371
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 400..409
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 438..447
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 476..485
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 514..523
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 592..601
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 651..660
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 689..698
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 802..811
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 881 AA; 96996 MW; 254A22369CD390D9 CRC64;
MSDSFESGDH GSFTESLLSV TQLAIESSTL SPVSHYGIDA ELKCESDSNC PKNSQCVDSF
CQCIPGHCRN SGQCLITSAS EVYCFCMNNF SGPECEFKNQ PCGSIYNCQN GAECVFDPSQ
NRSSCHCASG FHGDNCEYVD ESKTIEGCDT LICLNNGSCS IETNGSAICI CSLGFEGKTC
DRNIDDCANN PCHNGGICHD LINDYACECL HPYNGRNCTE TIDPCESEPC LNNGICETSK
DLLTFNCTCP IGFRGLTCEE NIDDCLGSNC TEGQICVDLL NAFECRCPLG YQGPRCQDRI
DHCQNHSCVH GHCSNNLLNY TCACEIGYEG IFCDQDIDEC QQNNPCINGL CVNKNGSFQC
YCTPGFTGVH CQIDIDECLS QPCQNNGHCI NLQSTYKCNC TNGYSGQNCE IEVDECKSNP
CANGGTCQDE LGSFTCLCPP GIEGPQCERD IDECLNKPCQ NGGTCVNQLP HYKCHCREGF
TGENCESDID ECEQNPCLNA AICINHNGSY ECKCESGFEG YHCEKNIDEC SSNPCQNNGK
CIDRIADFEC DCSGTGFEGR FCENEFNDCQ SNPCADGTLR CEDLHLNYSC VCLPGFTGRQ
CEIDIDECDN EPCQNGGTCE EKAHDFVKNY RDKYEIDELV NRVDLRYTCT CPSGFEGTNC
EINKDDCEMH NCQNGAICID EIDSYYCKCA LGFDGKHCQY LVDPCISSPC RNGATCKFQR
FIRFLGERCD RRRSCYSDCH PEFSHCVMKS HNFQLCACLP NSNGLYNRSL CDPIYDCNIA
PGLCHNGGTC TNSIGMGYYC TCPEGYEGLI CEKKKRINVL IVLIASIGIA LSIALLIILM
IVFRSVKRAR ATRGTYSPST QEMFGNSAGE ILKPPPEERL I
//
