ID A0A131ZTV3_SARSC Unreviewed; 366 AA.
AC A0A131ZTV3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 28-JUN-2023, entry version 26.
DE RecName: Full=Ataxin-10 {ECO:0000256|ARBA:ARBA00018804};
GN ORFNames=QR98_0004050 {ECO:0000313|EMBL:KPL99169.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPL99169.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPL99169.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPL99169.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- FUNCTION: Necessary for the survival of cerebellar neurons. Induces
CC neuritogenesis by activating the Ras-MAP kinase pathway. May play a
CC role in the maintenance of a critical intracellular glycosylation level
CC and homeostasis. {ECO:0000256|ARBA:ARBA00002116}.
CC -!- SIMILARITY: Belongs to the ataxin-10 family.
CC {ECO:0000256|ARBA:ARBA00008384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPL99169.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXLN01000643; KPL99169.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A131ZTV3; -.
DR VEuPathDB; VectorBase:SSCA009880; -.
DR OrthoDB; 5479391at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR019156; Ataxin-10_domain.
DR PANTHER; PTHR13255; ATAXIN-10; 1.
DR PANTHER; PTHR13255:SF0; ATAXIN-10; 1.
DR Pfam; PF09759; Atx10homo_assoc; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
FT DOMAIN 273..360
FT /note="Ataxin-10"
FT /evidence="ECO:0000259|Pfam:PF09759"
SQ SEQUENCE 366 AA; 43531 MW; 61969E8C02EB2BB7 CRC64;
MLVLKNELDR PIDKVSFDFV HRTLKLQYNL MRLSLLTRGE WIFENCWDFI FDQQYYRKLL
DLEKFSANEE NRSLQKNCCL VITALMYELL QHSTGHCQSF VDPIFDELDC NDKLDFWLLL
FNLVISEISE WALWIIFIAL KKKTFTRKLF SKLTVNYRLI LIDILQEFVE DEAKNANVKE
WNMKNLDYDS QYECFDRDII QNISDYLQQK TFHSNKECNQ EEIHLIIKSD KILIKLLLQL
QLLAKSEASI FAVKSRLDDL DESMNGINPV FGFKRDIIGL IANCLHKNRE GQDYLRESGA
LYALLECTRI DQNNPFIQQW CIFALRNALE ANESNQKFVQ NLQEQKIIYD EKLLDRIRFK
KKKTLA
//
