ID A0A131ZX35_SARSC Unreviewed; 909 AA.
AC A0A131ZX35;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Cell division cycle protein 27 homolog {ECO:0000256|ARBA:ARBA00039307};
GN ORFNames=QR98_0017970 {ECO:0000313|EMBL:KPM03366.1}, SSS_5075
GN {ECO:0000313|EMBL:KAF7489127.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM03366.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM03366.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM03366.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
RN [2] {ECO:0000313|Proteomes:UP000070412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=33001992;
RA Korhonen P.K., Gasser R.B., Ma G., Wang T., Stroehlein A.J., Young N.D.,
RA Ang C.S., Fernando D.D., Lu H.C., Taylor S., Reynolds S.L., Mofiz E.,
RA Najaraj S.H., Gowda H., Madugundu A., Renuse S., Holt D., Pandey A.,
RA Papenfuss A.T., Fischer K.;
RT "High-quality nuclear genome for Sarcoptes scabiei-A critical resource for
RT a neglected parasite.";
RL PLoS Negl. Trop. Dis. 14:0-0(2020).
RN [3] {ECO:0000313|EMBL:KAF7489127.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SSS_KF_BRIS2020 {ECO:0000313|EMBL:KAF7489127.1};
RA Korhonen P.K.K., Guangxu M.G., Wang T.W., Stroehlein A.J.S., Young N.D.,
RA Ang C.-S.A., Fernando D.W.F., Lu H.L., Taylor S.T., Ehtesham M.E.M.,
RA Najaraj S.H.N., Harsha G.H.G., Madugundu A.M., Renuse S.R., Holt D.H.,
RA Pandey A.P., Papenfuss A.P., Gasser R.B.G., Fischer K.F.;
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblMetazoa:KAF7489127.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
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DR EMBL; WVUK01000065; KAF7489127.1; -; Genomic_DNA.
DR EMBL; JXLN01004782; KPM03366.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A131ZX35; -.
DR EnsemblMetazoa; SSS_5075s_mrna; KAF7489127.1; SSS_5075.
DR VEuPathDB; VectorBase:SSCA009101; -.
DR OMA; YHETVNT; -.
DR OrthoDB; 152021at2759; -.
DR Proteomes; UP000070412; Unassembled WGS sequence.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:KPM03366.1};
KW Cell division {ECO:0000313|EMBL:KPM03366.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000070412};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 498..531
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 566..599
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 600..633
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 634..667
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 736..769
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 909 AA; 103238 MW; 72376B8F51E1CE6C CRC64;
MIIQEPIKAT ISFALENYAY ADAIFLAERL YAEVKNSDNL FLLATAYFRS GKPNIAYSIL
SRNKYVPQKS PNCHFLRARC CLQLTKYAEA VTLLLEPLSP NVMFSSKKFS QEEITSIYGE
LSSFVAQLLG QLLYKLEDFK LANYYLTLSL KLNPFLWSSF EKLLRIDPIK VDHEKIFSID
SFDLTYSCGT HPLIKLLNST QSLSDKVADN TKIDEKKSTD DSNYYFVTPE VPKNYSKKRI
ELSTPYAILK QSPGKNKVDV ITPESDGNWL KVTCLAPTKN ISRNVRSKFN TAVSSPSQQV
LMETSNLCGN RNISANDDSS RHTFGVLSLD QDTFNILSMD NLVNKKSSNN KLETQSKLSS
LARKTVQDSA MIIDDTTLSI TQPPILTRRS SRLNSDVGSI KENSSNSSEK IIRRVTPVKR
CRRTINFDKN KLNNENKSSS VTSLDINKTG VKAQRASANG LMELIEKFAK AFKFLAEYRC
QEAIECLNQL PKNHYKTGLV LSMIGRCYFE MGSYEESIEY FKSCRRLEPY RLDGLEFYST
ALWHLQRELE LSCLSQELIQ YDRFAPQTWC VAGNCFSLQK DHEISIKFLK RAIQVDPNFS
YAYTLLGHEL ISADELDNAM SCFNNATRID PRHYNAWCGV GLIFYKQEKY ENAAYHYRRA
LEISPFNPIL MCHLAIVSHH VNKSKEAIDL LNEASKLDPN NVLIKFHRAS IHFSLEDYNL
ALTELEELKK LVPKESMIYF LIGKIHKKLG DTHLAVMNFS WAVHIDPKGS ANQHKEFMEP
NQTSTNELVV HPSQTDGSDF SSTPGTTPFT QRSSFMNHGT MDSSGSFSNH IRNTSNIRTL
EESEEFNNLI DVEVDAEDEE SNLESNSIEF RNLPNELSSS ELFNASINSA DFNANTSTNS
SNNVNDFVM
//
