ID   A0A132A1U0_SARSC        Unreviewed;       597 AA.
AC   A0A132A1U0;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   28-JUN-2023, entry version 33.
DE   SubName: Full=NADPH-dependent diflavin oxidoreductase 1-like protein {ECO:0000313|EMBL:KPM05026.1};
GN   ORFNames=QR98_0034850 {ECO:0000313|EMBL:KPM05026.1};
OS   Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC   Sarcoptidae; Sarcoptinae; Sarcoptes.
OX   NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM05026.1, ECO:0000313|Proteomes:UP000616769};
RN   [1] {ECO:0000313|EMBL:KPM05026.1, ECO:0000313|Proteomes:UP000616769}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM05026.1};
RX   PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA   Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT   "Draft genome of the scabies mite.";
RL   Parasit. Vectors 8:585-585(2015).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPM05026.1}.
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DR   EMBL; JXLN01010058; KPM05026.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A132A1U0; -.
DR   VEuPathDB; VectorBase:SSCA003169; -.
DR   OMA; DIMSIPR; -.
DR   OrthoDB; 276396at2759; -.
DR   Proteomes; UP000616769; Unassembled WGS sequence.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.360; -; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR003097; CysJ-like_FAD-binding.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR001094; Flavdoxin-like.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR19384:SF10; NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1; 1.
DR   PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00667; FAD_binding_1; 1.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   PRINTS; PR00369; FLAVODOXIN.
DR   PRINTS; PR00371; FPNCR.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF52218; Flavoproteins; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   FMN {ECO:0000256|ARBA:ARBA00022643}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
SQ   SEQUENCE   597 AA;  70130 MW;  9321F383CB5BFC96 CRC64;
     MVAWSISRLD PSISIEFMAC DEYPIDRLIE ERFILFICST SGLGDVPLNM KSFWKFLLRK
     DLPRGVLYDL SFAIIGLGDS SYKHYNFVAK KLLKRLLYLG AENVLEFCLG DDQHEHGPFY
     TIDPWLEKFY QMLSPSNKFD PSESFTRLIN SSFVVKSLRS ESKNELDEEI ENINGFVDDS
     IKTGYHPLKP YEAVVVENKR MSTEDHFQDI RLISLELEVD MHYDVTDICV VYPENSAEDV
     DRFLDLFNKS DKEDAFRIDP NEIVRITLDT NRHNWIPKSS YYWRIVNKPI MIQEIITKYF
     DINAIPKRSF FDLFYRFSRN DLEREKLKSF ATGFDLEDLN EYVNRPKRTI LEVMSDFPFT
     TPYVPIDYLF DLIPSISPRS YSIASSPSHS TSLQILYGVV IYKTRLKKPR LGQCTNWMVR
     QKPNHSKLSI YFRPGSFVLP SPTTPIIMIA AGLGLAPFRA FILERTHNEE SVDCNYLFFG
     CRNKDKDYFI EKEFEKLIAA NLLRIYPAFS RQDPQQKIYV QDVVWIHRDL IFDLLFERKA
     NIYVAGKSQQ YPDLVREILA RIFKDKFDTD NTNLSHYDDI VDKFVREKRI QFECCLS
//