ID A0A132A7H4_SARSC Unreviewed; 319 AA.
AC A0A132A7H4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=COP9 signalosome complex subunit 3 {ECO:0000256|ARBA:ARBA00014878};
GN ORFNames=QR98_0054040 {ECO:0000313|EMBL:KPM06923.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM06923.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM06923.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM06923.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN3 family.
CC {ECO:0000256|ARBA:ARBA00007084}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM06923.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXLN01011156; KPM06923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132A7H4; -.
DR VEuPathDB; VectorBase:SSCA003611; -.
DR OMA; NHYHDLV; -.
DR OrthoDB; 5036at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR10758:SF1; COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Signalosome {ECO:0000256|ARBA:ARBA00022790}.
FT DOMAIN 97..265
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPM06923.1"
SQ SEQUENCE 319 AA; 36677 MW; D8D17D58458C3F8A CRC64;
TLLCHRLTDY LIKEDQPSKG LLPLSIAVTK IQESSTQLTS IHSDICKLAL LSKCFQPVLN
FLNVDITDIS RENDRYDVKY FLTYYYYGGM IYSILEQYER AFLFFQNAIS ITGTAISQIS
IESYKKYVLI SLLLYGKLQP MSKTVVTYLN RSIKPFCVPY NKIVVAYSND SIDDLQEICL
KFFKEFSKDS NIGLVKLVIA SLTKVRIKNL TKTFITLSLK DIAIKVNLPS PEAAEKQILQ
MIENGEIYAS INQKDGMVEF SDYSEKYDSL QMYKTIEHQS LIELKINQCI SLNEKLKQLD
YEVAINPKYI QKTHNDDSV
//
