ID A0A132A811_SARSC Unreviewed; 316 AA.
AC A0A132A811;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Uridine phosphorylase 1-like protein {ECO:0000313|EMBL:KPM07108.1};
GN ORFNames=QR98_0055920 {ECO:0000313|EMBL:KPM07108.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM07108.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM07108.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM07108.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- SIMILARITY: Belongs to the PNP/UDP phosphorylase family.
CC {ECO:0000256|ARBA:ARBA00010456}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM07108.1}.
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DR EMBL; JXLN01011322; KPM07108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132A811; -.
DR VEuPathDB; VectorBase:SSCA008768; -.
DR OMA; VQLCNPH; -.
DR OrthoDB; 22073at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004850; F:uridine phosphorylase activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd17763; UP_hUPP-like; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR InterPro; IPR010059; Uridine_phosphorylase_euk.
DR NCBIfam; TIGR01719; euk_UDPppase; 1.
DR PANTHER; PTHR43691:SF11; FI09636P-RELATED; 1.
DR PANTHER; PTHR43691; URIDINE PHOSPHORYLASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 3: Inferred from homology;
FT DOMAIN 59..311
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
FT BINDING 96
FT /ligand="phosphate"
FT /ligand_id="ChEBI:CHEBI:43474"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 144..147
FT /ligand="phosphate"
FT /ligand_id="ChEBI:CHEBI:43474"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 224
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
FT BINDING 226
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610059-50"
SQ SEQUENCE 316 AA; 35705 MW; 1D6DC1ADA87B0165 CRC64;
MNKFDDIEII YEDSPLDLNP DGRIKLRNPH MDCLESDFLY HLGLDTKKNN LKQMFGDVKF
ICMGGTAERM QDFAQLVANE LGIDGSPVDL AKDSHRYSMF KIGPVLSVSV RITHGMGVSS
LSILMHELFK VAHYADCKDL CFFRIGTSGG LGVPPGSIII TDKAVDELMR PFFELHISGK
IVRRSCRFDA KLIEELKEIA KKQSNQYETF TGTTMCAMDF YETQSRLDGA FCNYTKEDKQ
NFLQKLSKNG VKNIEMEALV FGSMCQMACV RGAIVCVTLL NRLDGDQIAS SKACLRELQN
RPQRLVLDYI KYKLSQ
//
