ID A0A132A9U3_SARSC Unreviewed; 590 AA.
AC A0A132A9U3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=NGFI-A-binding-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=QR98_0062270 {ECO:0000313|EMBL:KPM07728.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM07728.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM07728.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM07728.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NAB family. {ECO:0000256|ARBA:ARBA00008864}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM07728.1}.
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DR EMBL; JXLN01011833; KPM07728.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132A9U3; -.
DR VEuPathDB; VectorBase:SSCA006396; -.
DR OMA; IKQEAFS; -.
DR OrthoDB; 4181992at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.120.2010; NAB conserved domain 2; 1.
DR InterPro; IPR006989; NAB_co-repressor_dom.
DR InterPro; IPR039040; NAB_fam.
DR InterPro; IPR006988; Nab_N.
DR InterPro; IPR038398; NCD2_sf.
DR PANTHER; PTHR12623; NGFI-A BINDING PROTEIN; 1.
DR PANTHER; PTHR12623:SF10; NGFI-A-BINDING PROTEIN HOMOLOG; 1.
DR Pfam; PF04904; NCD1; 1.
DR Pfam; PF04905; NCD2; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 124..201
FT /note="Nab N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04904"
FT DOMAIN 313..444
FT /note="NAB co-repressor"
FT /evidence="ECO:0000259|Pfam:PF04905"
SQ SEQUENCE 590 AA; 66138 MW; BC9CC004E88DE9D1 CRC64;
MAERKNIATN SDDSDEYALF NVLGSDSDSS EEFDLDSSLN LWKIPNISVE RNSPNSVVND
SMPTNSFVTE SIAPKELDVE KNLSKSYVRT SNQLLRMNFN DIFHSHNRIL GRNLNGTIAM
TTQPSNESEL QLYRVLQRAN LLTYYDTFIC QGGDDVQQLY EAGEEEFLEI MALVGMAAKP
LHVRRLQKAL HEWATNPSLF QSPLVQPTTS ANQSDSPSSL PISSVSRSLP TVSSVSNTKC
FNTITSLPAS ISSSASPSSK NGNNSSSPSL SNSVFDANSV GCNQSISSSP NQFSQNQSNE
NIQPTSPSVT PILNESQIIR LAEAAESLVR SLPASFFDLK PPSSNNNNGN KKRIVKEIET
VMAMKESDSK RMDEIRKYAA IYGRFDCKRK PEKPLTLHEV SVNEAAAQIC SKIPMLLYRR
DELFPLARQV VRDSGYQYSK GHSRSQYIRF GDEQSLYHHL NNSSNQTSSH HESQTKRMRR
NQTLGVSSKL SLSAPTYSNS TKAVSNSQND RQRRYDRLEG IVDQLKSLGN KQEEIESQLK
EANEKKNFKI ITELQNELNL ITDHQMLLVN EKSQLEQQQQ QQQQNVDCPK
//
