ID A0A132AAZ2_SARSC Unreviewed; 612 AA.
AC A0A132AAZ2;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 08-NOV-2023, entry version 40.
DE SubName: Full=Tyrosine-protein phosphatase non-receptor type 11-like protein {ECO:0000313|EMBL:KPM08144.1};
GN ORFNames=QR98_0066580 {ECO:0000313|EMBL:KPM08144.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM08144.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM08144.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM08144.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM08144.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXLN01012231; KPM08144.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132AAZ2; -.
DR VEuPathDB; VectorBase:SSCA004611; -.
DR OMA; CEIDIHR; -.
DR OrthoDB; 2911650at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0048666; P:neuron development; IEA:UniProt.
DR CDD; cd09931; SH2_C-SH2_SHP_like; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46559:SF3; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE; 1.
DR PANTHER; PTHR46559; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11; 1.
DR Pfam; PF00017; SH2; 2.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SMART; SM00252; SH2; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF55550; SH2 domain; 2.
DR PROSITE; PS50001; SH2; 2.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
FT DOMAIN 1..86
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 96..190
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 217..511
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 426..502
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 612 AA; 70349 MW; 19D9073F85D09B76 CRC64;
MLVDRGVEGS FLVRPSSSHP GDFTLSVLGN GEVTHIKIQN TDDYYDLYGG EKFATLAELV
HHYTSKKGQL KERNNKDRVI ELKYPLISED PTSERWFHGS ISPKEAEKLI LEKGKNGSFL
VRESQSKLGD YVLTVRIDDK VSHVKIYCQQ SKYDVGGGEK FHSLTDLVEY YKRNPMVETS
GTVVNLRTPF NATKITASTI ENRVKILSKE NNGKTGFWEE FEYLQQQACK HLYSRKAGEK
PENRNKNRYK NILPCEYLNS DELNRIKIFI QVDYTRVTLK DGPNVDEQDS IQSSDYINAN
FIEVEDEYTN QPSKKVYIAT QGPLANTKND FWSMVWHEKC SIIVMTTKEI ERSKPKCVRY
WCDRDQTTKF GRVTVQTINE KTMLDYTLRE FKVFYDNNES ESRIVYHYHF MAWPDHGVPS
DPGCVLNFLH EVNCKQESIG DSKPIIVHCS AGIGRTGTFI VIDILIDLIN QHGLDCEIDI
QRTIQIIRTK RSGMVQTEAQ YKFVYLAVQH YVNTLQQRIQ AEHKSLQAGR EYTNIKYTNE
VGDRFTSYGI PVGVSHIIIN NSAINSNNFG KNDSMNSMLA QQQSDNNIVH QDVERPPIPP
RSNRLDVTES YS
//
