ID A0A132AJE3_SARSC Unreviewed; 496 AA.
AC A0A132AJE3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN ORFNames=QR98_0096810 {ECO:0000313|EMBL:KPM11114.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM11114.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM11114.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM11114.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM11114.1}.
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DR EMBL; JXLN01016509; KPM11114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132AJE3; -.
DR VEuPathDB; VectorBase:SSCA008043; -.
DR OMA; TWINTHM; -.
DR OrthoDB; 3078548at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF269; ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 20..484
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 496 AA; 54249 MW; 036AF5B23D524240 CRC64;
MNTVSIVEFT QLFIGGKFFD SNPKRSFSTI NPFDGKVIAN IQQASLDDIN LTVQVARKRF
EDWSQTSPSV RGRFLYKLAN LFDENIERIA SLDSLENGIP ITEMIHCTRA AAEILRFYAG
AVDKIKGETL PMDQQRWTMT VREPLGVCAI IIPWNSPTLM LAKTIGPALA TGNTVIVKPA
EQTSLSALFI AHLTTLAGLP GGVFNVLTGD GPNVGAHLAS HMDIDMITFT GSLEVGRKIM
AASAESNLKK VTLELGGKSP LVIFDDVDVE KAAQLSSNAI FVSNGQVCCC GSRTYVHEKI
YDRFLKECVK LAENRIVGDP MDPKTQHGPQ VDESAVEKIM TMIRSGLNQG ALLMTGGKKG
LKKSLSNGID DYFIQPTVFA NVDESMSIGQ EEIFGPVQSI IKFSSLDEII ERANKTKFGL
AAGIITNDIN KALKFARSVR AGTCWINCYF VVRPSTPFGG YKLSGVGREF GEEALRQYTE
TKTITINLDE SNYLFG
//
