ID A0A132BUL3_9RHOB Unreviewed; 435 AA.
AC A0A132BUL3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=UDP-N-acetyl-D-glucosamine 6-dehydrogenase {ECO:0000313|EMBL:KUP91896.1};
DE EC=1.1.1.136 {ECO:0000313|EMBL:KUP91896.1};
GN Name=wbpA {ECO:0000313|EMBL:KUP91896.1};
GN ORFNames=TRIHO_32000 {ECO:0000313|EMBL:KUP91896.1};
OS Tritonibacter horizontis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Tritonibacter.
OX NCBI_TaxID=1768241 {ECO:0000313|EMBL:KUP91896.1, ECO:0000313|Proteomes:UP000068382};
RN [1] {ECO:0000313|EMBL:KUP91896.1, ECO:0000313|Proteomes:UP000068382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O3.65 {ECO:0000313|EMBL:KUP91896.1,
RC ECO:0000313|Proteomes:UP000068382};
RA Poehlein A., Giebel H.A., Voget S., Brinkhoff T.;
RT "Genome sequence of the marine Rhodobacteraceae strain O3.65, Candidatus
RT Tritonibacter horizontis.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUP91896.1}.
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DR EMBL; LPUY01000082; KUP91896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132BUL3; -.
DR PATRIC; fig|1768241.3.peg.3344; -.
DR Proteomes; UP000068382; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0047004; F:UDP-N-acetylglucosamine 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KUP91896.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000068382}.
FT DOMAIN 328..428
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 435 AA; 47060 MW; 8136FFB05C5F2418 CRC64;
MTATQSTPDG RADPMAGEIC ILGLGYVGLP LAVEFGRIRP VVGFDIDTGR IMELSQGFDR
TGELDTAELA QARGLRLTSD LGEIAEATTY IVTVPTPIDQ TRRPDLGPLL AATRTVGQVL
KSGDTVIYES TVYPGATEED CVPLLEALSG LRMNVDFGVG YSPERINPGD KTRRLPDIVK
VTSGSSPEVA AQVDALYAQI VTAGTYRAES IRVAEAAKVI ENSQRDINIA LINELAMIFN
RMDIDTEAVL RAAGTKWNFL NFRPGLVGGH CIGVDPYYLT HKAQQMGYHP EILLSGRRLN
DGMGAYVAQQ MIKAMLQRRV QVVDARVLVM GLTFKENCPD LRNTRVIDVI TGLREFGVTV
DVFDPCADPD EAMREYGIEL VSAPGQGAYD GVVVAVGHAA FHALGAEGIR AFATPKGLVY
DLKYVLPADQ SDLRL
//
