ID A0A132MGB2_HYDSH Unreviewed; 177 AA.
AC A0A132MGB2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NADH-quinone oxidoreductase subunit J {ECO:0000256|RuleBase:RU004429};
DE EC=7.1.1.- {ECO:0000256|RuleBase:RU004429};
GN ORFNames=HSCHL_1933 {ECO:0000313|EMBL:PTQ54990.1}, KM312_01925
GN {ECO:0000313|EMBL:MBT9281412.1}, SA87_09490
GN {ECO:0000313|EMBL:OAR04734.1};
OS Hydrogenibacillus schlegelii (Bacillus schlegelii).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family X. Incertae Sedis; Hydrogenibacillus.
OX NCBI_TaxID=1484 {ECO:0000313|EMBL:PTQ54990.1, ECO:0000313|Proteomes:UP000244180};
RN [1] {ECO:0000313|EMBL:OAR04734.1, ECO:0000313|Proteomes:UP000243024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MA 48 {ECO:0000313|EMBL:OAR04734.1,
RC ECO:0000313|Proteomes:UP000243024};
RA Hemp J.;
RT "Draft genome sequence of Hydrogenibacillus schlegelii DSM 2000.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PTQ54990.1, ECO:0000313|Proteomes:UP000244180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL33 {ECO:0000313|EMBL:PTQ54990.1};
RA Kadnikov V.V., Mardanov A.V., Ivasenko D., Beletsky A.V., Karnachuk O.V.,
RA Ravin N.V.;
RT "Burning lignite coal seam in the remote Altai Mountains harbors a
RT hydrogen-driven thermophilic microbial community.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MBT9281412.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RBS10-49 {ECO:0000313|EMBL:MBT9281412.1};
RA Kadnikov V., Mardanov A.V., Beletsky A.V., Karnachuk O.V., Ravin N.V.;
RT "Metagenomic Analysis of the Microbial Community in the Underground Coal
RT Fire Area (Kemerovo Region, Russia) Revealed Predominance of Thermophilic
RT Members of the Phyla Deinococcus-thermus, Aquificae, and Firmicutes.";
RL Microbiology 0:0-0(2021).
CC -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur
CC (Fe-S) centers, to quinones in the respiratory chain. Couples the redox
CC reaction to proton translocation (for every two electrons transferred,
CC four hydrogen ions are translocated across the cytoplasmic membrane),
CC and thus conserves the redox energy in a proton gradient.
CC {ECO:0000256|RuleBase:RU004429}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) +
CC NAD(+); Xref=Rhea:RHEA:57888, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124;
CC Evidence={ECO:0000256|RuleBase:RU004429};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU004429};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU004429}.
CC -!- SIMILARITY: Belongs to the complex I subunit 6 family.
CC {ECO:0000256|ARBA:ARBA00005698, ECO:0000256|RuleBase:RU004429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PTQ54990.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JAHHQF010000039; MBT9281412.1; -; Genomic_DNA.
DR EMBL; JXBB01000012; OAR04734.1; -; Genomic_DNA.
DR EMBL; PEBV01000001; PTQ54990.1; -; Genomic_DNA.
DR RefSeq; WP_066200130.1; NZ_PEBV01000001.1.
DR AlphaFoldDB; A0A132MGB2; -.
DR STRING; 1484.SA87_09490; -.
DR OrthoDB; 9814997at2; -.
DR Proteomes; UP000243024; Unassembled WGS sequence.
DR Proteomes; UP000244180; Unassembled WGS sequence.
DR Proteomes; UP000748108; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.120.1200; NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ; 1.
DR InterPro; IPR001457; NADH_UbQ/plastoQ_OxRdtase_su6.
DR InterPro; IPR042106; Nuo/plastoQ_OxRdtase_6_NuoJ.
DR PANTHER; PTHR33269:SF5; NAD(P)H-QUINONE OXIDOREDUCTASE SUBUNIT 6, CHLOROPLASTIC; 1.
DR PANTHER; PTHR33269; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6; 1.
DR Pfam; PF00499; Oxidored_q3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU004429};
KW Membrane {ECO:0000256|RuleBase:RU004429};
KW NAD {ECO:0000256|RuleBase:RU004429};
KW Quinone {ECO:0000256|RuleBase:RU004429};
KW Reference proteome {ECO:0000313|Proteomes:UP000243024};
KW Transmembrane {ECO:0000256|RuleBase:RU004429};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004429};
KW Ubiquinone {ECO:0000313|EMBL:PTQ54990.1}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004429"
FT TRANSMEM 32..53
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004429"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004429"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004429"
FT TRANSMEM 141..163
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004429"
SQ SEQUENCE 177 AA; 18492 MW; BA02CDD1FD3FF254 CRC64;
MESNVVVFLT VAALALFGGV MMLSLRRVLH MALAVALSFL SVAGVFFLLG AEFLGVMQII
VYTGAVTVLA VFGIMLTRHD AVDVQTARGA VQRGLAGIVA AGGFLFLFYL LLRSPLEPDG
AGGPPVVSIG AIGEALFSPE FILAFELVGV MLLAALIGAV TVAREEAPEA DREEEGR
//
