GenomeNet

Database: UniProt
Entry: A0A132PKU0_9MYCO
LinkDB: A0A132PKU0_9MYCO
Original site: A0A132PKU0_9MYCO 
ID   A0A132PKU0_9MYCO        Unreviewed;       351 AA.
AC   A0A132PKU0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=AFM11_18230 {ECO:0000313|EMBL:KWX22864.1};
OS   Mycolicibacterium wolinskyi.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=59750 {ECO:0000313|EMBL:KWX22864.1, ECO:0000313|Proteomes:UP000070612};
RN   [1] {ECO:0000313|EMBL:KWX22864.1, ECO:0000313|Proteomes:UP000070612}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC_01 {ECO:0000313|EMBL:KWX22864.1,
RC   ECO:0000313|Proteomes:UP000070612};
RA   de Man T.J., Perry K.A., Coulliette A.D., Jensen B., Toney N.C.,
RA   Limbago B.M., Noble-Wang J.;
RT   "A draft genome sequence of Mycobacterium wolinskyi.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KWX22864.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; LGTW01000011; KWX22864.1; -; Genomic_DNA.
DR   RefSeq; WP_067851302.1; NZ_LGTW01000011.1.
DR   EnsemblBacteria; KWX22864; KWX22864; AFM11_18230.
DR   PATRIC; fig|59750.3.peg.1003; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000070612; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000070612};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070612};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       51    344       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   351 AA;  37415 MW;  D119E9E2FA4E2662 CRC64;
     MNLAQIANPP ATSDRRIRSF SAIPSPHDVL TEFPLGARRA ERVARDRDEI ADILAGRDDR
     LLVVVGPCSV HDPAAALEYA SRLVKVADEL KDRLKVVMRV YFEKPRTTIG WKGLINDPGM
     DGTFDVARGL RIARQLLLDI IDIGLPVGCE FLEPTSPQYI ADAVAWGAIG ARTTESQVHR
     QLASGLSMPV GFKNGTDGNI QVAVDGVKAA AAEHVFFGMD DLGRGAVVST EGNEDCHVIL
     RGGTDGPNYG TESVSDAAAK LSKAGLPGRV VIDCSHANSG KDHVRQAVVA TEVAAMVRDG
     APVSGVMLES FLVGGAQAPE ARPLTYGQSV TDKCMDWATT DLVLRELAKR P
//
DBGET integrated database retrieval system