ID A0A132PN28_9MYCO Unreviewed; 299 AA.
AC A0A132PN28;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:KWX23741.1};
DE EC=4.2.1.17 {ECO:0000313|EMBL:KWX23741.1};
GN ORFNames=AFM11_13235 {ECO:0000313|EMBL:KWX23741.1};
OS Mycolicibacterium wolinskyi.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=59750 {ECO:0000313|EMBL:KWX23741.1, ECO:0000313|Proteomes:UP000070612};
RN [1] {ECO:0000313|EMBL:KWX23741.1, ECO:0000313|Proteomes:UP000070612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC_01 {ECO:0000313|EMBL:KWX23741.1,
RC ECO:0000313|Proteomes:UP000070612};
RA de Man T.J., Perry K.A., Coulliette A.D., Jensen B., Toney N.C.,
RA Limbago B.M., Noble-Wang J.;
RT "A draft genome sequence of Mycobacterium wolinskyi.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could possibly oxidize fatty acids using specific components.
CC {ECO:0000256|ARBA:ARBA00002994}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:16105, ChEBI:CHEBI:15377, ChEBI:CHEBI:57318,
CC ChEBI:CHEBI:58856; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023709};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:20724, ChEBI:CHEBI:15377, ChEBI:CHEBI:58521,
CC ChEBI:CHEBI:137480; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023717};
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWX23741.1}.
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DR EMBL; LGTW01000007; KWX23741.1; -; Genomic_DNA.
DR RefSeq; WP_067849288.1; NZ_LGTW01000007.1.
DR AlphaFoldDB; A0A132PN28; -.
DR STRING; 59750.AWC31_03520; -.
DR PATRIC; fig|59750.3.peg.6740; -.
DR Proteomes; UP000070612; Unassembled WGS sequence.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR PANTHER; PTHR43802; ENOYL-COA HYDRATASE; 1.
DR PANTHER; PTHR43802:SF1; IP11341P-RELATED; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KWX23741.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000070612}.
FT REGION 274..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 32634 MW; 9B3750FFCFAFE603 CRC64;
MAHEFETLLY RTAAPVATIT LNRPDQLNTI VPPMPDEIEK AIGLAERDPE IKVIVLRGAG
RSFSGGYDFG GGFQHWGEAM NTDGRWDPGK DFAMVSARET GPTQKFMAIW RASKPVIAQV
HGWCVGGASD YALCADIVIA SDDAVIGTPY ARMWGAYLNG MWLYRLSLAK VKWHSLTGEP
LTGKEAAAVE LINESVPFEH LEARVAEIAG KLARIPLSQL QAQKLIVNQA YENMGLASTQ
TLGGILDGLM RNTPDALSFI DTAAHQGVRA AIERRDGPWG DYSEAPPERR PDPSHIIEP
//
