ID   A0A132T7M2_9MYCO        Unreviewed;       831 AA.
AC   A0A132T7M2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:KWX67359.1};
GN   ORFNames=ASJ79_21890 {ECO:0000313|EMBL:KWX67359.1};
OS   Mycobacterium sp. NAZ190054.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=1747766 {ECO:0000313|EMBL:KWX67359.1, ECO:0000313|Proteomes:UP000070146};
RN   [1] {ECO:0000313|EMBL:KWX67359.1, ECO:0000313|Proteomes:UP000070146}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAZ190054 {ECO:0000313|EMBL:KWX67359.1,
RC   ECO:0000313|Proteomes:UP000070146};
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KWX67359.1}.
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DR   EMBL; LMVQ01000119; KWX67359.1; -; Genomic_DNA.
DR   RefSeq; WP_067954839.1; NZ_LMVQ01000119.1.
DR   AlphaFoldDB; A0A132T7M2; -.
DR   OrthoDB; 8445630at2; -.
DR   Proteomes; UP000070146; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR002656; Acyl_transf_3_dom.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF01757; Acyl_transf_3; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070146};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        588..609
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        636..655
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        667..686
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        692..708
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        715..732
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        790..810
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          448..533
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   831 AA;  90711 MW;  4BEA0FE92F0ACD84 CRC64;
     MRTLVDHLRG HGDRAAVFTR DQQLSYHDLA ERVEAFARTL GPRRRLVLLE TRNDVTTLVG
     YLGALAAGHV VLPVPAGRDH TNIIATYRPD VVVDAAGVHV HSEAARDLHD DLALLMSTSG
     STGSPKLVRL SRTNLLANAR SIVEYLQIRE TDRAATTLPM SYCYGLSVIH SHLLAGAALI
     LTEQSVADDG FWELFTHHRG TTFAGVPYTF ELLDRVGFQS KHLPHLRCVT QAGGRMPPER
     VRKYAALAAG QGWQLFVMYG ATEATARMAY LPPELALTRS NAIGRPVPGG AFTIEPVDEW
     AEPGTGELVY RGANVMMGYA HTPADLARGA ELDALRTGDI ARRGEDGLYE VVGRRSRFVK
     MYGLRLDLAQ IETTLAGAGV HALCTDNGDR LAVVATDEHD PDDVRRQTAE AAGVPAAVVD
     TVCVADLPKL ASGKPDYPTA RVLAAGAARS APRGGDLREV FAEVLLLDPA EIDEDASFVD
     LGGNSLTYVT MSARLERALG HLPTDWPQLP LRALRNLPAP KRRRWQSWGH TLETSVALRA
     VAIVLIVGSH AELFELWGGA HILLGVAGYN FGRFCLTPLP RPDRIRHLRA TIAWVAIPSV
     VWVAFALMVT DDYHASNLLL ANKFLGPHDS MTAGRLWFVE VLVWTLIALA VLFCVPAMDR
     LERRHPFGIA MSFLAFGMLL RYGVLAGDTR DAWFTVLAFW FFAAGWAAAK AAHTWQRALV
     TAVLFIGLLG YFDDPLRQTM VFAGLALLIW LPAVRCPSGV AAVAAVLAEA SLYIYLTHYQ
     VYPLFGSHEL IGVVAALVVG ITVAATVTLA RQWWRDRGVR LPDRARAPAL R
//