ID A0A132T960_9MYCO Unreviewed; 1062 AA.
AC A0A132T960;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:KWX67566.1};
GN ORFNames=ASJ79_21335 {ECO:0000313|EMBL:KWX67566.1};
OS Mycobacterium sp. NAZ190054.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1747766 {ECO:0000313|EMBL:KWX67566.1, ECO:0000313|Proteomes:UP000070146};
RN [1] {ECO:0000313|EMBL:KWX67566.1, ECO:0000313|Proteomes:UP000070146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAZ190054 {ECO:0000313|EMBL:KWX67566.1,
RC ECO:0000313|Proteomes:UP000070146};
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KWX67566.1}.
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DR EMBL; LMVQ01000106; KWX67566.1; -; Genomic_DNA.
DR RefSeq; WP_067954449.1; NZ_LMVQ01000106.1.
DR AlphaFoldDB; A0A132T960; -.
DR OrthoDB; 5476461at2; -.
DR Proteomes; UP000070146; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000070146}.
FT DOMAIN 63..189
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 1062 AA; 115878 MW; 1A2F947637BC61A5 CRC64;
MNDDDVPTPI DDLLNRAVQA INRGDRRTAD ALADQVLAAD DGNQDAEDLL TAPDEQGEIR
RLTIMFADLV DSTALSTRVE PEVYRTVIGR YREEVVRLVD HYEGHVASVK GDGLLVLFGH
PKAHENDAHR AVYAGLDIVR AIAELSERVQ RRFGFGISVR VGVHRGLVYL DTVHDDIYGL
GANYAARVCS VADPGSVAVS EAIELVVRDT FHTDVRAPQA VKGVPEPITT FRVLGERDVV
VGTAGPLVGR EPELAHLRSC WEQARHHALG TPGVAFQGEG GVGKTRLAYA AVEMAQRDGA
VVLGLFGSPF HTDVGLRPVR RLLERRCGIQ RESDPAHRLR ALENEVLQRS LRPEVVVPLL
APVLGIRAES GYQAVQSEGA KLSARIAGAV LDYLRACLDS GPALVLADDV HWFDPDTVAV
LTTLLGVDTG KLMVVITGRT LPPLGDRVTE FTVQPLDDAE AEELAGKLHP ELSGDARRAV
RTRCDGIPLY IEEVVAHLKD QTLGDDWATA VPDTLYEALF ARLRADPDAL RFVGAAALIG
SRFDKGLLSR VLGLDHDVIE TTLTGLAQAR VVEPVDKESW RFRHELLREV AVEVSPPTVR
RRLHSRIADA LVAGADRADP EWSLLAQHYE SAARYGEAAT AYEHASTDAR RRGALTEARA
HLAKALADVA MEKPGLVRDH REIELRLESG HLASAAQGHS SPEAVAEFER CLELIGPDPS
PELYATLNAL WVYYTARGDL RRSTQLAETL QAKVGKSPKA APGMATTMGI LAGFRGDFHA
ARDMLEKAAA SVRDTPAPSS FTYYGPNDPI GGMYSFLAFV RFVQGDLDGA EDALMLMEAR
SQAVGFPRGA FSLCYGRSIE ALVRSESGQP AVCAELASGL ISLARQYDFD EWVMVGWSQQ
SSGLAMAALA EGRTDRAVLG PHIETMRTVV RTWRAFDVMT FLAMSDAVLA RLLIAVGDLD
EARDCLDVSL KMGQDTWIQF YDAELLRLRA QTFPDRETRH EQLCSSLELA RSQGAHLLGL
RSATDDFVLM GDTARQTLRD AVQRLPEGSR LPEVSRARAL LR
//
