ID A0A133SG56_9FIRM Unreviewed; 232 AA.
AC A0A133SG56;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Precorrin-2 C(20)-methyltransferase {ECO:0000313|EMBL:KXA68680.1};
GN ORFNames=HMPREF3201_01787 {ECO:0000313|EMBL:KXA68680.1};
OS Megasphaera sp. MJR8396C.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=1603888 {ECO:0000313|EMBL:KXA68680.1, ECO:0000313|Proteomes:UP000070314};
RN [1] {ECO:0000313|EMBL:KXA68680.1, ECO:0000313|Proteomes:UP000070314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MJR9396C {ECO:0000313|EMBL:KXA68680.1,
RC ECO:0000313|Proteomes:UP000070314};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|PIRNR:PIRNR036427}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXA68680.1}.
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DR EMBL; LRVC01000093; KXA68680.1; -; Genomic_DNA.
DR RefSeq; WP_062412581.1; NZ_KQ958202.1.
DR AlphaFoldDB; A0A133SG56; -.
DR STRING; 1603888.HMPREF3201_01787; -.
DR PATRIC; fig|1603888.3.peg.1715; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000070314; Unassembled WGS sequence.
DR GO; GO:0030788; F:precorrin-2 C20-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11645; Precorrin_2_C20_MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR012382; CobI/CbiL.
DR InterPro; IPR006364; CobI/CbiL/CobIJ_dom.
DR NCBIfam; TIGR01467; cobI_cbiL; 1.
DR PANTHER; PTHR43467; COBALT-PRECORRIN-2 C(20)-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43467:SF2; COBALT-PRECORRIN-2 C(20)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036427; Precrrn-2_mtase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KXA68680.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KXA68680.1}.
FT DOMAIN 5..215
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 232 AA; 24852 MW; BDEED6C3F087665E CRC64;
MMKGKLYCVG IGPGDPELLT VKALKTIGAC PVLAVPKSGS GPLTAKDILL KALDDCDLTL
SDKKVLTLDF PMTRKDEVLA GAHEKAAKAV MADLDEGRDV ALITLGCPTV YATSIYVHHL
VQEAGYETAI VPGVPSFCAV AAKLQQPLCE KDEALLIIPG NHEQRRQLLA LPGSKVIMKP
SGKLKPIQDE LKDLGLLERT SMIERCGLSG EKIYEQAADA EETGYFAVLL VK
//
