ID A0A133SI59_9FIRM Unreviewed; 446 AA.
AC A0A133SI59;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Branched-chain amino acid transport system carrier protein {ECO:0000256|RuleBase:RU362122};
GN ORFNames=HMPREF3201_01158 {ECO:0000313|EMBL:KXA69375.1};
OS Megasphaera sp. MJR8396C.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=1603888 {ECO:0000313|EMBL:KXA69375.1, ECO:0000313|Proteomes:UP000070314};
RN [1] {ECO:0000313|EMBL:KXA69375.1, ECO:0000313|Proteomes:UP000070314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MJR9396C {ECO:0000313|EMBL:KXA69375.1,
RC ECO:0000313|Proteomes:UP000070314};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids. {ECO:0000256|RuleBase:RU362122}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362122};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362122}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000256|ARBA:ARBA00008540, ECO:0000256|RuleBase:RU362122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXA69375.1}.
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DR EMBL; LRVC01000046; KXA69375.1; -; Genomic_DNA.
DR RefSeq; WP_062412084.1; NZ_KQ958176.1.
DR AlphaFoldDB; A0A133SI59; -.
DR STRING; 1603888.HMPREF3201_01158; -.
DR PATRIC; fig|1603888.3.peg.1118; -.
DR Proteomes; UP000070314; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR NCBIfam; TIGR00796; livcs; 1.
DR PANTHER; PTHR30588; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR PANTHER; PTHR30588:SF0; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW ECO:0000256|RuleBase:RU362122};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362122};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362122};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362122};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362122}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 40..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 119..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 152..170
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 275..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
SQ SEQUENCE 446 AA; 47035 MW; AAAA2F67124486C1 CRC64;
MGENKGNRTV AIGLMLFALF FGAGNLIFPA AMGQAAGINV WWAVLGFVVT GVGLPLAGVL
AMGYSGCKNL QELAGRVHPA YGLFFTVISY LTIGPFFAIP RTGSVSYEIA VRPFLQSGGS
EAIMTGFLVL FFLISLWLSI SPQKLVDRIG KILTPALLLA ILLLIAKSFI TPLGSPQEPI
AAYGTASIAA VQGILDGYNT MDAIASLVFA ILVIEFVMED GATTPSAITR EVFKAGAIAV
GCLGFVYIFV AKIGADSVAA FGIQETGAPV LSKSAMILFG NAGAVILAII VLLACLSTAI
GLITSCASYF NELIKIGYKK WVVIFTLISF FVAMFGLKTI ITAAIPVLMF IYPLVVAIII
LAFLHNAFGG RQCVYAWTIG LTLIPAIVTG LQTAEFSLGH IDTIFATMVP LHSLGMGWVC
FTIAGFVIGF IWKSIFSSSS NGVTAK
//
