ID A0A133UEZ9_9EURY Unreviewed; 560 AA.
AC A0A133UEZ9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Pyruvate ferredoxin oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AKJ66_03610 {ECO:0000313|EMBL:KXA92755.1};
OS candidate division MSBL1 archaeon SCGC-AAA259E22.
OC Archaea; Euryarchaeota; candidate division MSBL1.
OX NCBI_TaxID=1698265 {ECO:0000313|EMBL:KXA92755.1, ECO:0000313|Proteomes:UP000070657};
RN [1] {ECO:0000313|EMBL:KXA92755.1, ECO:0000313|Proteomes:UP000070657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC-AAA259E22 {ECO:0000313|EMBL:KXA92755.1};
RX PubMed=26758088; DOI=10.1038/srep19181;
RA Mwirichia R., Alam I., Rashid M., Vinu M., Ba-Alawi W., Anthony Kamau A.,
RA Kamanda Ngugi D., Goker M., Klenk H.P., Bajic V., Stingl U.;
RT "Metabolic traits of an uncultured archaeal lineage -MSBL1- from brine
RT pools of the Red Sea.";
RL Sci. Rep. 6:19181-19181(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXA92755.1}.
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DR EMBL; LHXP01000048; KXA92755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133UEZ9; -.
DR PATRIC; fig|1698265.3.peg.751; -.
DR Proteomes; UP000070657; Unassembled WGS sequence.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000070657}.
FT DOMAIN 13..167
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 200..428
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
SQ SEQUENCE 560 AA; 61533 MW; 0DE85DDD3A500202 CRC64;
MEGELSVVMG GEAGDGVRAA GGVLGRILNR HGLYSFLRED YQSLIRGGHN YSQVRASKEK
VRSQIEEADI VVALDERSVE NHEWRLMEKG KLIFDPDELE YSSEKATPLP LSSMVEEAEG
IEIMKNSAAI GAISYFYDLS LEIVENVMGK VYGEKAEKNI VLAHKGHEFC KDNYEKVKDL
ECPDREMTPL LTGNQAISLG AVKAGLDVYI AYPMTPSTSI LHFTASHQDD LGLTVVQPEN
EIGVINMALG SAYAGARAMV ASSGGGFSLM QESMSLAGMS ETPILVIECQ RAGPSTGVPT
YTAQSDMDLA MCFGQGEFPS IVLAPGDTEE AFYRAGEGLN LAWKYQVPVV LLSDKHLSES
SMSTELELDK VSPEEAKIEK NPDSDYERYR FTEDGVSPLA FPGSPDTVVK TTSYEHIEFG
YTTEDPAEIE AMQDKRKRKW GGIEKDVMRR EPVKVYGDEN SDKLILGWGS TKGAILEAMK
LIDSPTKFVQ PIYLRPFPSK IVGDYIDGAS KTVCVENNAT GQLAKLIRGE TLKTVDEKVL
KYDARPFNPP DLAKKLEVLL
//
