ID A0A133V5S9_9EURY Unreviewed; 362 AA.
AC A0A133V5S9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=AKJ41_00015 {ECO:0000313|EMBL:KXB01800.1};
OS candidate division MSBL1 archaeon SCGC-AAA259O05.
OC Archaea; Euryarchaeota; candidate division MSBL1.
OX NCBI_TaxID=1698271 {ECO:0000313|EMBL:KXB01800.1, ECO:0000313|Proteomes:UP000070344};
RN [1] {ECO:0000313|EMBL:KXB01800.1, ECO:0000313|Proteomes:UP000070344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC-AAA259O05 {ECO:0000313|EMBL:KXB01800.1};
RX PubMed=26758088; DOI=10.1038/srep19181;
RA Mwirichia R., Alam I., Rashid M., Vinu M., Ba-Alawi W., Anthony Kamau A.,
RA Kamanda Ngugi D., Goker M., Klenk H.P., Bajic V., Stingl U.;
RT "Metabolic traits of an uncultured archaeal lineage -MSBL1- from brine
RT pools of the Red Sea.";
RL Sci. Rep. 6:19181-19181(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB01800.1}.
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DR EMBL; LHXV01000001; KXB01800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133V5S9; -.
DR Proteomes; UP000070344; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR NCBIfam; NF040721; Trm14_Arch; 1.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000070344};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 42..153
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 362 AA; 41642 MW; D0910F62A07D41BC CRC64;
MELLATTIRG LESIAIEEIE DLRGEKACFE HEGMVRLSGR EEDVFKLNYL SKTLHRVLIL
LSSFKVRSLE DVYRRCKEID FSCYLNSSQK FAVRAKRTGA HGFTSMDLES EIGQAIVDSF
QEEGSRIEVD LENPDVYIRS ELRGEEVWVA IDTTGGESLH KRGYRSYEHP APLKPTIAHC
LVRLSEWEED ETLLDPMCGS GTICIEAWHW KNEVPNWFRD DYAFWRLPFL DREKFRDLKE
KYDSRARSRS LPVRGCDVSE KHVRGAKRNI TSAGADIQIS TSNATEVSLD ANKIVTNPPY
GIRIGSKRKV KNLYEDFASN LADYQWDRAV ILTGRPDYMP KEGLEERIDF HYGNLPSSIL
IF
//
