ID A0A133VIS1_9EURY Unreviewed; 955 AA.
AC A0A133VIS1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AKJ52_02315 {ECO:0000313|EMBL:KXB06341.1};
OS candidate division MSBL1 archaeon SCGC-AAA382C18.
OC Archaea; Euryarchaeota; candidate division MSBL1.
OX NCBI_TaxID=1698281 {ECO:0000313|EMBL:KXB06341.1, ECO:0000313|Proteomes:UP000070404};
RN [1] {ECO:0000313|EMBL:KXB06341.1, ECO:0000313|Proteomes:UP000070404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCGC-AAA382C18 {ECO:0000313|EMBL:KXB06341.1};
RX PubMed=26758088; DOI=10.1038/srep19181;
RA Mwirichia R., Alam I., Rashid M., Vinu M., Ba-Alawi W., Anthony Kamau A.,
RA Kamanda Ngugi D., Goker M., Klenk H.P., Bajic V., Stingl U.;
RT "Metabolic traits of an uncultured archaeal lineage -MSBL1- from brine
RT pools of the Red Sea.";
RL Sci. Rep. 6:19181-19181(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB06341.1}.
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DR EMBL; LHYF01000041; KXB06341.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133VIS1; -.
DR PATRIC; fig|1698281.3.peg.445; -.
DR Proteomes; UP000070404; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013701; DEAD/DEAH_assoc.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08494; DEAD_assoc; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000070404}.
FT DOMAIN 9..37
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 40..217
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 259..406
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT MOTIF 9..37
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
SQ SEQUENCE 955 AA; 109035 MW; 88172C7667D488D9 CRC64;
MKTHNISKTM DQFKHLHEKV KEPLKKFGIT KPTPIQRRAI PPVLKGKNSL LVAPTGTGKT
EAALLPIFSQ YVEKDTENGI KIIYIAPLRA LNRDMLDRLQ RWEEHLDLDI QVRHGDTTQY
QRRQQALHPP DILITTPETM QAILPGSRMK EHLKSVRWVI VDEVHELAES KRGTQLSLGL
ERVFRLAGDF QRVGLSATVG DMEKMSRFLV GPEREVEIVN ASSTEEMSIW VESPMPTESD
AELSDDLNAD PSTIARIRRI RDLIDEHESS LTFVNTREAS EILGSRLKFW DSDFPVSVHH
GSLSKDYRIS SEDEFRKGGV KSIICTSSME LGIDIGNIDF VIQYMSPRQV KRLIQRVGRS
GHKIREASEG VVIAADPDDV IEAGMIAERV VSDWLEPTDI HEKSLDVLAH QIVGFTLDGV
SDPEKIFEFV SRAYPYRNFP SEEFFEVVEQ LQDQGVLWRD DGEISRGKRS WKYYYTTLSM
IPDIKNFQIE DMVTGQSIGT LDEEFVIDKA EPGVTFICQG EAWQVVEIED DKVRVEPIDD
PYGAIPAWEG ELIPVDSKIA EKSGIFRKHV KNALADGEDK DGILEDLESR YPVEKDALEW
SLNYLEDQDE EAYIPTDDGL LIETYKDFAV LHVPLGTNGN RTMGQILSAL LTTRLGASVR
IKTDPYRIAF RFPDKPDPEL IETTLRDLEP DYIEPLLEKI LKKSSVFRWR LLHVAKKFGA
IEKDADYSKI SGDRLVEAYQ DTPLWTEAER EVRLEKLNVP VVKKLLESLE NDEIEIETIS
RGYNQGPTPI GLPILNELAA SGELVVPERA EREILKALKR RLKNEQIKLL CLNCLDWSTL
TRVRRLDEKP ECGNCGARLL GLTPKRGREV RKLLEKERRE EKLDDEEKHR IKRFKDTANM
IITHGKKAIT AMAGRGIGPT TASRILRKQP ETEDDFYREI LDAERQYART HGFWD
//
