ID   A0A133YFS2_9FIRM        Unreviewed;       367 AA.
AC   A0A133YFS2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Site-specific recombinase, phage integrase family {ECO:0000313|EMBL:KXB42035.1};
GN   ORFNames=HMPREF1872_00510 {ECO:0000313|EMBL:KXB42035.1};
OS   Amygdalobacter nucleatus.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Amygdalobacter.
OX   NCBI_TaxID=3029274 {ECO:0000313|EMBL:KXB42035.1, ECO:0000313|Proteomes:UP000070080};
RN   [1] {ECO:0000313|Proteomes:UP000070080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KA00274 {ECO:0000313|Proteomes:UP000070080};
RA   Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA   O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA   Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000256|ARBA:ARBA00003283}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXB42035.1}.
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DR   EMBL; LSCV01000008; KXB42035.1; -; Genomic_DNA.
DR   RefSeq; WP_066713498.1; NZ_KQ959571.1.
DR   AlphaFoldDB; A0A133YFS2; -.
DR   STRING; 1497955.HMPREF1872_00510; -.
DR   PATRIC; fig|1497955.3.peg.490; -.
DR   OrthoDB; 9785687at2; -.
DR   Proteomes; UP000070080; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd01189; INT_ICEBs1_C_like; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR028259; AP2-like_int_N.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF14657; Arm-DNA-bind_4; 1.
DR   Pfam; PF14659; Phage_int_SAM_3; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070080};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT   DOMAIN          167..350
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   367 AA;  43179 MW;  5B6919FE965DF3EE CRC64;
     MPAYKDEKNG KWFVSFYYKD WDGQSRKKLK RGFETKKEAI TYERNFTVKM SGSLNMLFED
     YFELYKADVI GTIRLNTWMT KEHMIRTKIL PFFTGMKVSE IKPVVVKKWH NVLLNIENAE
     GEAYKPTYLK SIHAQLSCMF NHAVKYYGLR QNPCKVTGRI GKQKSDEEVE FWTKDEYLQF
     IEAVKDKDIS FYAFEILYWT GIRLGELRAL TKGDFDFDKK TMRISKSAQR INGEEVITDP
     KTPKSKRTIM LPDFLIRELQ DYFLKIGYFS EDEQIFPKCK TYFNKEMERG IKKSGVKKIK
     LHALRHSHIS LLIEMGFTPV DIAARTGHES IKVLMDYSHM FPNKQVDMAD KLDKEGEYSE
     STEISKL
//