ID A0A133YIA7_9BACT Unreviewed; 633 AA.
AC A0A133YIA7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ATP-dependent DNA helicase, RecQ family {ECO:0000313|EMBL:KXB42928.1};
GN ORFNames=HMPREF1870_01315 {ECO:0000313|EMBL:KXB42928.1};
OS Bacteroidales bacterium KA00344.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX NCBI_TaxID=1497954 {ECO:0000313|EMBL:KXB42928.1, ECO:0000313|Proteomes:UP000070254};
RN [1] {ECO:0000313|Proteomes:UP000070254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KA00344 {ECO:0000313|Proteomes:UP000070254};
RA Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB42928.1}.
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DR EMBL; LSCT01000120; KXB42928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133YIA7; -.
DR STRING; 1497954.HMPREF1870_01315; -.
DR PATRIC; fig|1497954.3.peg.1338; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000070254; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KXB42928.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000070254}.
FT DOMAIN 27..195
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 219..365
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 633 AA; 72588 MW; BE5734B825D14573 CRC64;
MKTDSYLKIL RQYWGYDSFR GIQREIIESI GSGKDTLGLM PTGGGKSITF QVPAMAQEGL
CVVVTPLIAL MKDQVQHLRD KGIRATAIYS GMSRHEIVKS LDNCILGDIK LLYVSPERIG
SAIFQTKIRK MNVSFITVDE AHCISQWGYD FRPSYLRIAE IRKLLPNAPV LALTATATPQ
VIGDIQKQLS FKAENVFHMS FERRNLAYVV RVATDKEREL VHILSSVNGS AIVYVRSRRR
CKDVSAMLEQ NGISSTFYHA GLEPTIKDER QKQWKQDKKR VMVATNAFGM GIDKPDVRTV
VHMDCPDSIE AYFQEAGRAG RDKNKAYAVL LWNNSDHRKL NKRIADNFPE KDFIRDVYEH
LAYYYVIGVG SGSEHTFSFE IDKFCHIYKY FPLRVNAALR LLQNAGYLEY EMDPDSSARL
MFLLGRNELY RLNELTSHEE AVITAILRNY GSLFTDYGYI DEALIAMEAG IGRELTYQVL
KTLSGKHILH FIPQRKTPYI TYTQNRVDES DVIIPRNVYE NRKDQFAKRI EAMIEYATND
KVCRSRQLLR YFGEANTHDC NVCDVCLDNK PNYSSSKATT EAQEQIMTLL NDKQKHKIDE
LHQLNISQSQ LDKALQHLVN EELIHLDGVF IYL
//
