ID A0A133ZDR1_9FIRM Unreviewed; 231 AA.
AC A0A133ZDR1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Stage 0 sporulation protein A homolog {ECO:0000256|ARBA:ARBA00018672};
GN ORFNames=HMPREF1866_02636 {ECO:0000313|EMBL:KXB53564.1};
OS Lachnoanaerobaculum saburreum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=467210 {ECO:0000313|EMBL:KXB53564.1, ECO:0000313|Proteomes:UP000070394};
RN [1] {ECO:0000313|EMBL:KXB53564.1, ECO:0000313|Proteomes:UP000070394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00896 {ECO:0000313|EMBL:KXB53564.1,
RC ECO:0000313|Proteomes:UP000070394};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play the central regulatory role in sporulation. It may
CC be an element of the effector pathway responsible for the activation of
CC sporulation genes in response to nutritional stress. Spo0A may act in
CC concert with spo0H (a sigma factor) to control the expression of some
CC genes that are critical to the sporulation process.
CC {ECO:0000256|ARBA:ARBA00024867}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB53564.1}.
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DR EMBL; LSDA01000140; KXB53564.1; -; Genomic_DNA.
DR RefSeq; WP_040457947.1; NZ_KQ959848.1.
DR AlphaFoldDB; A0A133ZDR1; -.
DR STRING; 467210.HMPREF1866_02636; -.
DR PATRIC; fig|467210.3.peg.2611; -.
DR OrthoDB; 9790442at2; -.
DR Proteomes; UP000070394; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.250.690; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; REGULATOR OF RPOS; 1.
DR PANTHER; PTHR48111:SF76; TRANSCRIPTIONAL REGULATORY PROTEIN WALR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..116
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 130..231
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 130..231
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 231 AA; 26698 MW; A67FC2839C7CDC6E CRC64;
MNKALVVDDE KLIVKGIKFS LEQDGYEVDV AYDGKEALRM AKEKEYDIVL LDVMLPEMDG
MEVCQAIREF SEMPIIMLTA KGTDMDKILG LEYGADDYIT KPFNILEVKA RIKAIIRRNS
KKSKAADKND RIIEVSDLKL DLDSRRVFEK GKEVNLTAKE FDILELLTQN PDKVYSREQL
LNIVWGNKLH EAGDVRTVDV HVRRLREKIE PNPSEPKYIH TKWGVGYYFK E
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