ID A0A133ZG97_9ACTN Unreviewed; 585 AA.
AC A0A133ZG97;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Putative phosphoribosylformylglycinamidine synthase {ECO:0000313|EMBL:KXB54465.1};
DE Flags: Fragment;
GN ORFNames=HMPREF3190_00030 {ECO:0000313|EMBL:KXB54465.1};
OS Coriobacteriales bacterium DNF00809.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales.
OX NCBI_TaxID=1588753 {ECO:0000313|EMBL:KXB54465.1, ECO:0000313|Proteomes:UP000070490};
RN [1] {ECO:0000313|Proteomes:UP000070490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00809 {ECO:0000313|Proteomes:UP000070490};
RA Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB54465.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSCX01000002; KXB54465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A133ZG97; -.
DR STRING; 1588753.HMPREF3190_00030; -.
DR PATRIC; fig|1588753.3.peg.30; -.
DR Proteomes; UP000070490; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02203; PurL_repeat1; 1.
DR Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR InterPro; IPR041609; PurL_linker.
DR InterPro; IPR010918; PurM-like_C_dom.
DR InterPro; IPR036676; PurM-like_C_sf.
DR InterPro; IPR036921; PurM-like_N_sf.
DR PANTHER; PTHR10099; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR PANTHER; PTHR10099:SF1; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR Pfam; PF02769; AIRS_C; 1.
DR Pfam; PF18072; FGAR-AT_linker; 1.
DR SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE 4: Predicted;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755};
KW Reference proteome {ECO:0000313|Proteomes:UP000070490}.
FT DOMAIN 206..249
FT /note="Phosphoribosylformylglycinamidine synthase linker"
FT /evidence="ECO:0000259|Pfam:PF18072"
FT DOMAIN 455..583
FT /note="PurM-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02769"
FT REGION 154..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 585
FT /evidence="ECO:0000313|EMBL:KXB54465.1"
SQ SEQUENCE 585 AA; 64029 MW; 405E7DBE1C627DA0 CRC64;
MGMRVYVRRK LHFNVEEQQT LHEFQHVLGI RNLTDIAIFI RYDIDGMPQE AFNQCLNTVM
SDPVSDVCTT ELPHGNYAAV FGVEFLPGQF DQRADSASEC IQLINPAYRP DVHTAKIYCL
SGDISNEQLA RIKHHLINPV ECQEISDVNA PWERTSAGQG ANVGAAEDET SKGETSNCKA
NASSALVETI SGFISFTSDE LHACGARLGL SIDDADLACA QAYFAREQRD PTITELKVID
TYWSDHCRHT TFETQLNDIR IDDPTIQATY NTYMSLRNDL HIQKPVRLMD IATIAAKYLV
NKGVLTNLDI SDEINACTTH VTVDVDGELQ DWLFLFKNET HNHPTEIEPF GGAATCIGGC
IRDPLSGRAY VYQAMRVTGS ADPRTPLNQT LPGKLPQRTI TTMAQAGYSS YGNQIGLATG
LVHELYHPGY RAKRMEVGAC VGAVPASHVK RRKPQAGDVI VLVGGRTGRD GIGGASGSSK
QHTQTSLSTC GAEVQKGNAP VERKIQRLFR NPNVSRMIIR CNDFGAGGVS VAVCEIADGV
TINLNRVPKK YSGLTGTELA LSESQERMAV ALASEDVEPF LHYAH
//
