ID   A0A133ZLR9_9FIRM        Unreviewed;       449 AA.
AC   A0A133ZLR9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=HMPREF1866_01904 {ECO:0000313|EMBL:KXB56396.1};
OS   Lachnoanaerobaculum saburreum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Lachnoanaerobaculum.
OX   NCBI_TaxID=467210 {ECO:0000313|EMBL:KXB56396.1, ECO:0000313|Proteomes:UP000070394};
RN   [1] {ECO:0000313|EMBL:KXB56396.1, ECO:0000313|Proteomes:UP000070394}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DNF00896 {ECO:0000313|EMBL:KXB56396.1,
RC   ECO:0000313|Proteomes:UP000070394};
RA   Oliw E.H.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXB56396.1}.
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DR   EMBL; LSDA01000102; KXB56396.1; -; Genomic_DNA.
DR   RefSeq; WP_060931584.1; NZ_KQ959836.1.
DR   AlphaFoldDB; A0A133ZLR9; -.
DR   STRING; 467210.HMPREF1866_01904; -.
DR   PATRIC; fig|467210.3.peg.1885; -.
DR   OrthoDB; 1641940at2; -.
DR   Proteomes; UP000070394; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF11; LICHENAN PERMEASE IIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        33..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        302..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          9..430
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   449 AA;  48927 MW;  FABD47684EFDAB29 CRC64;
     MFDKIAAFLD KNLSTPMAKL SEQRHLRAIR DGIIATLPIV VVSSLFLVIA FLPNQMPASW
     GIAQFIKANA GRILLPYRMA MYIMTLYAVF GIGFSLAKSY DLDGLSGAIL SELAFLLTVV
     PVSLPEATDE ITNLAANNQA LADYIKAVPE GWHLGMSYIG SDGMFVGIIS AFIAVEIYRF
     TQKSGFKIRM PEQVPASVAR SFEALTPTVI ILLLFSTVTM WLGIKVHDIV GSIIRPIVNV
     ADTLPSVLLL TFLDSFFWCF GIHGSSVVGS LTRPVWLMLL EQNSNAFAAG AAIPNIAPEP
     FYQWFIYIGG SGTTIGLAIL LLLRSRSQYG KTLGKVAFVP ALFNINEPMI FGCPIILNPV
     LLIPFVLNPI ICAIIAWIAT ELGLVNRVVA SVPWTLPGPI GAFLATNGDI RALILNVLLI
     ILSILIYLPF FNKYDADLKK QEDSGEVSV
//