ID A0A133ZY93_9FIRM Unreviewed; 377 AA.
AC A0A133ZY93;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:KXB60417.1};
GN ORFNames=HMPREF1866_00603 {ECO:0000313|EMBL:KXB60417.1};
OS Lachnoanaerobaculum saburreum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=467210 {ECO:0000313|EMBL:KXB60417.1, ECO:0000313|Proteomes:UP000070394};
RN [1] {ECO:0000313|EMBL:KXB60417.1, ECO:0000313|Proteomes:UP000070394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00896 {ECO:0000313|EMBL:KXB60417.1,
RC ECO:0000313|Proteomes:UP000070394};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXB60417.1}.
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DR EMBL; LSDA01000014; KXB60417.1; -; Genomic_DNA.
DR RefSeq; WP_060930544.1; NZ_KQ959776.1.
DR AlphaFoldDB; A0A133ZY93; -.
DR STRING; 467210.HMPREF1866_00603; -.
DR PATRIC; fig|467210.3.peg.595; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000070394; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 2..362
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
FT COILED 248..275
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 377 AA; 42150 MW; CE258E5FDF17C4F7 CRC64;
MIYMDNASTT VVDKEAFDMA KKYLFENYAN PSSSYSMAND VKADMEDARD MIADILGARY
NEIYFTSGGS ESNNWAILKS CELMENKGKH IISSKIEHHS VLHTLSYLEK KGYEVTYLST
DEKGIIDINE LKSAIREDTV LISIMFANNE IGTIEPIKEI GKIAREHNIL FHTDAVQAVG
HLPIDVNELN IDLLSASGHK FHSPKGVGFL YIRSGIKLTS LIHGGSQERN RRAGTENTFG
IVAMANAMKN CYEHLKEYNI QMQTLRDELL SLILKNIEGS HLNGCMHNRL SNNINIYFEN
INGELLLILL NQNGVCASLG SACTTGSIDP SHVIMAISND KKRASSSLRL TLSKYTTKDE
VNTTFEVLKK CINQLRK
//
