ID A0A135I4V0_9GAMM Unreviewed; 302 AA.
AC A0A135I4V0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Methylenetetrahydrofolate reductase {ECO:0000256|RuleBase:RU003862};
GN ORFNames=ATN88_22150 {ECO:0000313|EMBL:KXF80455.1};
OS Enterovibrio coralii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Enterovibrio.
OX NCBI_TaxID=294935 {ECO:0000313|EMBL:KXF80455.1, ECO:0000313|Proteomes:UP000070529};
RN [1] {ECO:0000313|EMBL:KXF80455.1, ECO:0000313|Proteomes:UP000070529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CAIM 912 {ECO:0000313|EMBL:KXF80455.1,
RC ECO:0000313|Proteomes:UP000070529};
RA Gomez-Gil B., Enciso-Ibarra J.;
RT "Genomic Taxonomy of the Vibrionaceae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU003862};
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777, ECO:0000256|RuleBase:RU003862}.
CC -!- SIMILARITY: Belongs to the methylenetetrahydrofolate reductase family.
CC {ECO:0000256|RuleBase:RU003862}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXF80455.1}.
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DR EMBL; LNTY01000051; KXF80455.1; -; Genomic_DNA.
DR RefSeq; WP_067419350.1; NZ_LNTY01000051.1.
DR AlphaFoldDB; A0A135I4V0; -.
DR STRING; 294935.ATN88_22150; -.
DR OrthoDB; 4367389at2; -.
DR UniPathway; UPA00193; -.
DR Proteomes; UP000070529; Unassembled WGS sequence.
DR GO; GO:0004489; F:methylenetetrahydrofolate reductase (NAD(P)H) activity; IEA:UniProtKB-EC.
DR GO; GO:0006555; P:methionine metabolic process; IEA:InterPro.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.220; -; 1.
DR InterPro; IPR029041; FAD-linked_oxidoreductase-like.
DR InterPro; IPR003171; Mehydrof_redctse-like.
DR Pfam; PF02219; MTHFR; 1.
DR SUPFAM; SSF51730; FAD-linked oxidoreductase; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU003862};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003862};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003862};
KW Reference proteome {ECO:0000313|Proteomes:UP000070529}.
SQ SEQUENCE 302 AA; 34228 MW; DAAAC22FED25BDD6 CRC64;
MLLDKIKARE SGIILYGLVP PKKGTESEKV TEIASRQVAR LQDQPIDGLI VYDIQDEATR
TSEERPFPFM ETLDGVEYSR DYLADIKLPR VIYRSVGKYS EASLSRFLED SHPADELSVF
VGASSADQSV TMPMSEAYAL KKRVNKDMLL GGVTIPERHL VKGDEHLRVF RKIEAGCSFF
VSQGVYDVHA SKDFLSDYYY YGKKHGIPLV PIIFTLTPCG SQKTLQFMKW LGINIPRWLE
NDLIHSDDIL QQSVDYSEQS WRELKEFADE KGIPIGCNIE SVAVRKVEVD ASIELLNRIK
AI
//
