ID A0A135LAJ9_PENPA Unreviewed; 744 AA.
AC A0A135LAJ9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=PGRI_048640 {ECO:0000313|EMBL:KXG46008.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG46008.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG46008.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG46008.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC clathrin to receptors in coated vesicles. Clathrin-associated protein
CC complexes are believed to interact with the cytoplasmic tails of
CC membrane proteins, leading to their selection and concentration.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG46008.1}.
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DR EMBL; LHQR01000069; KXG46008.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LAJ9; -.
DR STRING; 5078.A0A135LAJ9; -.
DR OMA; NPPEVQW; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000070168};
KW Transport {ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 15..533
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT REGION 638..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 81330 MW; C617F4B1B5C9D280 CRC64;
MAMNKIRGAF AVPRKGETFE LRAGLVSQYA YERKESIQKT IMAMTLGKDV SALFPDVLKN
IATADLEQKK LVYLYLMNYA KSHPDLCILA VNTFVQDSED PNPLIRALAI RTMGCIRVEK
MVDYMEEPLR KTLRDESPYV RKTAAICVAK LFDLNPTMAL ENGFLETLQE MIGDPNPMVV
ANSVTALQEI QHTAPETQAL QINSNSLRKM LMALNECTEW GRVTILSTLA EYKTADVKES
EHICERVAPQ FQHVNSGVVL AAVKAVFLHM KNVNPELSKT YLKKMAPPLV TLVSSAPEVQ
YVALRNIDLL LQKEPEILNK ELRVFFCKYN DPQYVKFQKL EIMVRIANDR NVDQLLAELK
EYALEVDMDF VRRAVKAIGQ VAIKIESASE RCVNTLLDLI NTKVNYVVQE AIVVIKDIFR
KYPGYEGIIP TLCQCIDELD EPNARAALIW IVGEYAEKIS NAGDILGGFV DGFNEEFSST
QLQILTAVVK LFLKRPEKAQ GLVQRVLQAA TSENDNPDVR DRAYIYWRLL SNTSDSNATK
NIVLSDKPPI VTTIHSLPTT LLDQLLSELS TLSSVYHKPP EQFVGHGRFG ADAVMRAAIE
EQIQNARENP LAAAAAAAAG GTTAPAQAQN NVENLLDIDF DGGAPASAQS QPSSGMSGLE
GLAGTPVRVA SPAAGTPTGQ ASNNLDDLLG VFGDSGAAQP SSGANSGGGA DLMNGFSGLD
LSGNAGPSQN NQSKKSNEDI LSLF
//
