ID A0A135LQG7_PENPA Unreviewed; 358 AA.
AC A0A135LQG7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Polyketide synthase, enoylreductase {ECO:0000313|EMBL:KXG51215.1};
GN ORFNames=PGRI_067870 {ECO:0000313|EMBL:KXG51215.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG51215.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG51215.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG51215.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG51215.1}.
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DR EMBL; LHQR01000044; KXG51215.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LQG7; -.
DR STRING; 5078.A0A135LQG7; -.
DR OMA; GPKFEAK; -.
DR OrthoDB; 2267374at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000070168}.
FT DOMAIN 27..354
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 358 AA; 38099 MW; 0C7789A23BFBB989 CRC64;
MKALISNRSL ATRFFNLATG KSVCGQGGQV KDVPIPTISP DEILVKVKAV ALNPTDFKHL
DVVSPPHSII GCDYAGVVQQ VGSAVKGWTP GDRVAGAVHG GLFPDKGSFA EYLKVDSDLA
WKIPDGISDT DATTYGVSAV TAMLTLNVRH GLPFVQGDEA SPKDEAIFIY AGATSAGLYH
IQIAKAAGYK VVTTASPRSF DLVKEYGATA VFDYRSETVA ADIVKAYPNI SKAVDCFSEG
KSTSVCAEVL KNTGGTVMML LPNGKSSVPG VEYELVMAYT LFGRPFQWLP PIGPKFEAKP
ADREALARFY KNLPTITHIL KPIPTTKQKE GFEGILDGLN KLRAGTVSGG KLVVEFPA
//
