ID A0A135LQX4_PENPA Unreviewed; 1105 AA.
AC A0A135LQX4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=phosphoinositide 5-phosphatase {ECO:0000256|ARBA:ARBA00013044};
DE EC=3.1.3.36 {ECO:0000256|ARBA:ARBA00013044};
GN ORFNames=PGRI_093900 {ECO:0000313|EMBL:KXG51378.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG51378.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG51378.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG51378.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- SIMILARITY: Belongs to the synaptojanin family.
CC {ECO:0000256|ARBA:ARBA00008943}.
CC -!- SIMILARITY: In the central section; belongs to the inositol 1,4,5-
CC trisphosphate 5-phosphatase family. {ECO:0000256|ARBA:ARBA00009678}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG51378.1}.
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DR EMBL; LHQR01000031; KXG51378.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LQX4; -.
DR STRING; 5078.A0A135LQX4; -.
DR OMA; HPCHELR; -.
DR OrthoDB; 996872at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR002013; SAC_dom.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF257; PHOSPHOINOSITIDE 5-PHOSPHATASE; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF02383; Syja_N; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50275; SAC; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000313|EMBL:KXG51378.1};
KW Exonuclease {ECO:0000313|EMBL:KXG51378.1};
KW Hydrolase {ECO:0000313|EMBL:KXG51378.1};
KW Nuclease {ECO:0000313|EMBL:KXG51378.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000070168}.
FT DOMAIN 146..517
FT /note="SAC"
FT /evidence="ECO:0000259|PROSITE:PS50275"
FT REGION 934..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1105 AA; 123119 MW; 5B2909E3BA4345F9 CRC64;
MSNLRVLCRD QPQRTIALVS SDHALVFHYT STDTSAKDSP RCQVEFSDLE EVDLQGYRPL
GYGYGTLGLV TLNEDVFVCV VTSSSQAATV RPGETVSRID NVGFYCLNRS EYEYGLEHET
ASQFAAEERL GTDGKDVVTD HPFLALKKLL GDGSFYYSLD FNLTDRLQDR ANKLVAFDID
TLDEDMLWNS YMISPLLFFR SHLPPSDKAK LDASQMLTCV IRGFASTLKV PATISILPHV
RTNFPSMLTI ISRQSSRRAG TRFNSRGIDD DGHVANFVET ETILWISPGI VFSYAQVRGS
VPIFWEQAPG LIPGQQKIEV TRSSDATQHA FNKHFESLEL EYGAVHVVNL LSELKPGEAE
LSCKFRQHIN KSSTRQKEGD GTSPHRSLLR MTEYDFLAET RGPSGYEASS QIKHELINSL
DEFSYFLSED SGRPNKTSYD GADAVNNSSV ILQQEGVFRT NCLDCLDRTN LVQTIISSMA
FETFLSQQGG SLSSDLQVRH STIWADNGDA LSKIYAGTGA LKSSFTRHGK MSLAGALADA
RKSATRLYVN NFTDKAKQKT IDLLLGRLTN QLPVYLYDPI NDLVIEELSH RTPEYSSRKQ
VRFWVGTFNV NGRDEGPGTD LTPWLFPGSD ESDEDPAIFV VGFQEIVALS PQQIMSTDPS
TRKVWERAVY DCLNAHSKMK GTGKYVHLRS GQLVGAAVLL YVKEDSLKYI KNVEGSTGLS
GIAGNKGGCA VRFDFSNTSV CFVTAHLAAG FANYDERNRD YEIIDRGLRF QKNRSIADHD
AVIWLGDFNY RIGLGNPSVR ELILQRDYRR LYDNDQLNLQ MVAGRVFQFY SEGPIEFPPT
YKYDVGRDSY DTSEKARIPA WCDRILWRGS SLRQTNYQTA DLKVSDHRPV WATFDCVIDI
VNYTLKESLR RSIYEEKQGH GHTSLADSVS LLDLDDDDET TPHVSIAPGL PPASSDRSRW
WLDNGASVKA TVQPPKQGYI PNPQRKSNPF SADVDWVLSP DSIENKNAEP IPVTKKSMLP
PRRDTSESFT ESLLPQADGT KKVRPAVPRK PLSLSSQGKV GTVSPSSQHT SRQDSPGDGV
TAGMGSTDLL SDSGSEQIEW KPLFQ
//
